Compound

(3Z)-dodecenoyl-CoA

An acyl-CoA(4−) species arising from deprotonation of the phosphate and diphosphate OH groups of cis-dodec-3-enoyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:58543), read 2026-09-23. CC BY 4.0.

CHEBI:58543ChEBI

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Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C33H52N7O17P3S
Mass: 943.8 g/mol
Charge: -4
InChIKey: XEMIVMKTVGRFTD-REDSNERGSA-J
SMILES: CCCCCCCC/C=CCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

What the reference databases state

Statements

14 statements

14 statements · 2 reference databases · Subject: (3Z)-dodecenoyl-CoA · Sources: Human-GEM, Rhea

Order

(3Z)-dodecenoyl-CoA is converted to (2E)-dodecenoyl-CoACompoundHuman-GEM MAR03355Inferred only
(3Z)-dodecenoyl-CoA is converted to (2E)-dodecenoyl-CoACompoundHuman-GEM MAR03239Inferred only
(2E)-dodecenoyl-CoA is converted to (3Z)-dodecenoyl-CoACompoundHuman-GEM MAR03239Inferred only
(2E)-dodecenoyl-CoA is converted to (3Z)-dodecenoyl-CoACompoundHuman-GEM MAR03355Inferred only
CHEBI:1146900 is converted to (3Z)-dodecenoyl-CoACompoundHuman-GEM MAR03237Inferred only
CHEBI:1146900 is converted to (3Z)-dodecenoyl-CoACompoundHuman-GEM MAR03353Inferred only
(3Z)-dodecenoyl-CoA is a substrate of ECH1ProteinHuman-GEM MAR03239Inferred only
(3Z)-dodecenoyl-CoA is a substrate of ECI1ProteinHuman-GEM MAR03239Inferred only
(3Z)-dodecenoyl-CoA is a substrate of ECI1ProteinHuman-GEM MAR03355Inferred only
(3Z)-dodecenoyl-CoA is a substrate of ECI2ProteinHuman-GEM MAR03239Inferred only
(3Z)-dodecenoyl-CoA is a substrate of ECI2ProteinHuman-GEM MAR03355Inferred only
(3Z)-dodecenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR03355Inferred only

Show the remaining 2

(3Z)-dodecenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03355Inferred only
(3Z)-dodecenoyl-CoA is a substrate of HADHBProteinRhea RHEA:47460Inferred only

Reactions

7 reactions

MAM00885m+CHEBI:1146900(3Z)-dodecenoyl-CoA+CHEBI:15351
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211GO:0005759
Human-GEM MAR03237CC BY 4.0Reference data
(2E)-dodecenoyl-CoA(3Z)-dodecenoyl-CoA
Catalysed by ECH1 or ECI1 or ECI2
Reaction pageReversibleBalancedEC 5.3.3.8, 5.3.3.-GO:0005759
Human-GEM MAR03239CC BY 4.0Reference data
MAM00885x+CHEBI:1146900(3Z)-dodecenoyl-CoA+CHEBI:15351
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16GO:0005777
Human-GEM MAR03353CC BY 4.0Reference data
(2E)-dodecenoyl-CoA(3Z)-dodecenoyl-CoA
Catalysed by ECI2 & HADHA & ECI1 & EHHADH
Reaction pageReversibleBalancedEC 5.3.3.8GO:0005777
Human-GEM MAR03355CC BY 4.0Reference data
(5Z)-tetradecenoyl-CoA+CHEBI:1146900+FAD+water+NAD(+)(3Z)-dodecenoyl-CoA+CHEBI:15351+FADH2+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH & ACOX1
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05119CC BY 4.0Reference data
(3Z)-dodecenoyl-CoA(2E)-dodecenoyl-CoA
Catalysed by ECI1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:23716CC BY 4.0Reference data
3-oxo-(5Z-tetradecenoyl)-CoA+coenzyme A(4-)(3Z)-dodecenoyl-CoA+acetyl-CoA
Catalysed by HADHB
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47460CC BY 4.0Reference data

Other names

1 name

Resolves to: (3Z)-dodecenoyl-CoA

Systematic name: 3'-phosphonatoadenosine 5'-{3-[(3R)-4-({3-[(2-{[(3Z)-dodec-3-enoyl]sulfanyl}ethyl)amino]-3-oxopropyl}amino)-3-hydroxy-2,2-dimethyl-4-oxobutyl] diphosphate}