acetylcholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

506 compounds within 3 steps: 4 in 1, 81 in 2, 421 in 3

Two steps

(S)-lactic acidReach from here →
1. Acetylcholine aectylhydrolase
2. transport of acetate and L-lactate (cytosol to extracellular)
Catalysed by BCHE, ACHE, SLC16A4, SLC16A5 and 4 morecytosol, extracellular spaceOne of 2 routes
N-(acetyl)-sphing-4-enineReach from here →
1. Acetylcholine aectylhydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
Catalysed by BCHE, ACHE, ASAH1cytosol
gamma-Glu-AlaReach from here →
1. transport of acetylcholine and GSH (cytosol to extracellular)
2. gamma-glutamyltransferase (alanine)
Catalysed by SLCO1A2, SLCO1B3, GGT1, GGT5 and 4 moreextracellular space, cytosol
3,3',5-triiodo-L-thyronineReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
prostaglandin E1Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of prostaglandin E1 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
prostaglandin I2Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of prostaglandin I2 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
prostaglandin F2alphaReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of prostaglandin F2alpha (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
prostaglandin H2Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of prostaglandin H2 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
prostaglandin D2Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of prostaglandin D2 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. transport of acetylcholine and GSH (cytosol to extracellular)
2. Glutathione: 15-HPETE oxidoreductase
Catalysed by SLCO1A2, SLCO1B3, GPX5, GPX1 and 7 moreextracellular space, cytosol
leukotriene A4Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of leukotriene A4 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
(R)-S-lactoylglutathioneReach from here →
1. transport of acetylcholine and GSH (cytosol to extracellular)
2. (R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)
Catalysed by SLCO1A2, SLCO1B3, GLO1, GLOD4extracellular space, cytosolOne of 2 routes
N-acetyl-D-glucosamine 6-phosphateReach from here →
1. Acetylcholine aectylhydrolase
2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
Catalysed by BCHE, ACHE, AMDHD2cytosol
S-formylglutathioneReach from here →
1. transport of acetylcholine and GSH (cytosol to extracellular)
2. alcohol dehydrogenase (formaldehyde)
Catalysed by SLCO1A2, SLCO1B3, ADH1C, ADH1A and 4 moreextracellular space, cytosol
dehydroepiandrosterone 3-sulfateReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of dehydroepiandrosterone sulfate (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 2 routes
leukotriene C4Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of leukotriene C4 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 6 routes
N-acetylputrescineReach from here →
1. Acetylcholine aectylhydrolase
2. N-acetylputrescine + H2O = putrescine + acetate
Catalysed by BCHE, ACHE, HDAC10cytosol
glutathione disulfideReach from here →
1. transport of acetylcholine and GSH (cytosol to extracellular)
2. Glutathione: 5-HPETE oxidoreductase
Catalysed by SLCO1A2, SLCO1B3, GPX5, GPX1 and 7 moreextracellular space, cytosolOne of 13 routes
taurolithocholate 3-sulfateReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
histamineReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of histamine (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
L-thyroxineReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
N(8)-acetylspermidineReach from here →
1. Acetylcholine aectylhydrolase
2. N(8)-acetylspermidine + H2O = spermidine + acetate
Catalysed by BCHE, ACHE, HDAC10cytosol
an N-acetyl-L-cysteine-S-conjugateReach from here →
1. Acetylcholine aectylhydrolase
2. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
Catalysed by BCHE, ACHE, ACY3cytosol
S-sulfanylglutathioneReach from here →
1. transport of acetylcholine and GSH (cytosol to extracellular)
2. Sulfide:glutathione,quinone oxidoreductase
Catalysed by SLCO1A2, SLCO1B3, SQORextracellular space, cytosol, mitochondrial matrix
dopamineReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of dopamine (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
glycolithocholate 3-sulfateReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
estrone 3-sulfateReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of estrone 3-sulfate (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 2 routes
prostaglandin E2Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of prostaglandin E2 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
L-cysteinylglycineReach from here →
1. transport of acetylcholine and GSH (cytosol to extracellular)
2. glutathione gamma-glutamylaminopeptidase
Catalysed by SLCO1A2, SLCO1B3, GGTLC3, GGT1 and 4 moreextracellular space, cytosolOne of 4 routes
(R)-noradrenalineReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of noradrenaline (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
ursodeoxycholateReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1A2extracellular space, cytosolOne of 4 routes
prostaglandin G2Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of prostaglandin G2 (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
thromboxane B2Reach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes
taurochenodeoxycholateReach from here →
1. transport of acetylcholine (cytosol to extracellular)
2. solute carrier organic anion transporter (S-glutathionyl-2-4-dinitrobenzene)
Catalysed by SLCO1B3, SLCO1A2, SLC7A9extracellular space, cytosolOne of 4 routes

Three steps

(S)-3-hydroxybutanoateReach from here →
Catalysed by BCHE, ACHE, SLC16A4, SLC16A5 and 4 morecytosol, extracellular space
(S)-carnitineReach from here →