N-(9Z,12Z-octadecadienoyl)-glycine
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
532 compounds within 3 steps: 2 in 1, 102 in 2, 428 in 3
Three steps
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
- (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
- (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
- (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + 2 glutathione = (17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + glutathione disulfide + H2O
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
- a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione = a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- Beta Oxidation of Fatty Acid
- 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA = 1-octanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by GLYATL2, ACADM, ACADS, MOGAT2 and 1 moremitochondrial matrix
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of cysteine and glycine (cytosol to extracellular)
- S-sulfanyl-L-cysteine + L-cysteine = S-disulfanyl-L-cysteine + L-alanine
Catalysed by GLYATL2, SLC3A2, SLC7A5, SLC7A8 and 1 moreextracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- acetyl-CoA C-acyltransferase (3-oxomyrist-7-enoyl-CoA)
Catalysed by GLYATL2, BAAT, HADHA, ACAA2 and 1 moreperoxisome, mitochondrial matrixOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- long-chain-fatty-acid-CoA ligase (cis-cetoleic acid)
Catalysed by GLYATL2, BAAT, SLC27A2, ACSL4 and 6 moreperoxisome, cytosolOne of 6 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- long-chain-fatty-acid-CoA ligase ((7Z)-tetradecenoic acid)
Catalysed by GLYATL2, BAAT, SLC27A2, ACSL4 and 6 moreperoxisome, cytosolOne of 9 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- Fatty Acid Beta Oxidation (C18:4->C16:4), Mitochondrial
Catalysed by GLYATL2, BAAT, HADHA, ACADVL and 1 moreperoxisome, mitochondrial matrixOne of 3 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- fatty acyl-CoA desaturase (N-C18:2CoA -> N-C18:3CoA)
- (6Z,9Z,12Z)-octadecatrienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA + reduced [electron-transfer flavoprotein]
Catalysed by GLYATL2, FADS1, FADS2, ACADL and 2 morecytosolOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- Fatty Acid Beta Oxidation Trans (C18:2->C16:2), Mitochondrial
- (7Z,10Z)-hexadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z,10Z)-hexadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]
Catalysed by GLYATL2, HADHA, ACADVL, HADHB and 2 moremitochondrial matrix
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- Fatty Acid Beta Oxidation (C12:3->C10:2), Mitochondrial
Catalysed by GLYATL2, BAAT, ECHS1, ACAA2 and 1 moreperoxisome, mitochondrial matrixOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- Fatty Acid Beta Oxidation (C10:2->C8:1), Mitochondrial
Catalysed by GLYATL2, BAAT, ECHS1, ACAA2 and 1 moreperoxisome, mitochondrial matrixOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- Glycodeoxycholate amidohydrolase
- Glycodeoxycholate amidohydrolase
Catalysed by GLYATL2cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of chloride and glycine (cytosol to extracellular)
- Peroxidase
Catalysed by GLYATL2, SLC6A9, SLC6A14, LPOextracellular space, cytosolOne of 4 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- Beta Oxidation of Fatty Acid
- Octanoyl-CoA hydrolase
Catalysed by GLYATL2, ACADM, ACADS, ACOT7mitochondrial matrix, cytosolOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of chloride and glycine (cytosol to extracellular)
- transport of chloride (cytosol to extracellular)
Catalysed by GLYATL2, SLC6A9, SLC6A14, SLC12A2 and 1 moreextracellular space, cytosolOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- medium-chain acyl-CoA ligase (hexanoic acid)
Catalysed by GLYATL2, BAAT, ACSM4, ACSM1 and 4 moreperoxisome, cytosolOne of 7 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- long-chain-fatty-acid-CoA ligase (elaidate)
Catalysed by GLYATL2, BAAT, SLC27A2, ACSL4 and 6 moreperoxisome, cytosolOne of 6 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of glycine and tryptophan (cytosol to extracellular)
- L-Tryptophan, Tetrahydrobiopterin:Oxygen Oxidoreductase (5-Hydroxylating)
Catalysed by GLYATL2, SLC7A5, TPH1, TPH2extracellular space, cytosolOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
- Glutathione: 5-HPETE oxidoreductase
Catalysed by GLYATL2, GSS, GPX5, GPX1 and 7 morecytosolOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- bile acid-CoA: amino acid N-acyltransferase
- Propanoyl-CoA:acetyl-CoA C-acyltransferase
Catalysed by GLYATL2, BAAT, ACAA1, SCP2 and 1 moreperoxisomeOne of 7 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of alanine and glycine (cytosol to extracellular)
- L-selenocysteine selenide-lyase (L-alanine-forming)
Catalysed by GLYATL2, SLC3A2, SLC7A5, SLC7A10 and 1 moreextracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of cysteine and glycine (cytosol to extracellular)
- N-acetylglutamate synthase (N-acetyl-L-cysteine)
Catalysed by GLYATL2, SLC3A2, SLC7A5, SLC7A8 and 1 moreextracellular space, cytosol, mitochondrial matrix
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- Hippurate (Benzoylglycinate) Formation
- N-benzoylglycine(out) + a dicarboxylate(in) = N-benzoylglycine(in) + a dicarboxylate(out)
Catalysed by GLYATL2, SLC22A6, SLC22A8mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of cysteine and glycine (cytosol to extracellular)
- K(+)(in) + L-cysteine(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-cysteine(in) + 3 Na(+)(in) + H(+)(in)
Catalysed by GLYATL2, SLC3A2, SLC7A5, SLC7A8 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of cysteine and glycine (cytosol to extracellular)
- L-Cysteine:tRNA(Cys) ligase (AMP-forming)
Catalysed by GLYATL2, SLC3A2, SLC7A5, SLC7A8 and 1 moreextracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of glycine and phenylalanine (cytosol to extracellular)
- L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)
Catalysed by GLYATL2, SLC7A5, FARSB, FARSAextracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of glycine and tryptophan (cytosol to extracellular)
- L-Tryptophan -tRNA(Trp) ligase (AMP-forming)
Catalysed by GLYATL2, SLC7A5, WARS1extracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of glycine and isoleucine (cytosol to extracellular)
- L-Isoleucine:tRNA(Ile) ligase (AMP-forming)
Catalysed by GLYATL2, SLC7A5, IARS1extracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of glutamine and glycine (cytosol to extracellular)
- L-Glutamine:tRNA(Gln) ligase (AMP-forming)
Catalysed by GLYATL2, SLC7A5, QARS1extracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of citrulline and glycine (cytosol to extracellular)
- L-citrulline + H(+) = isocyanate + L-ornithine
Catalysed by GLYATL2, SLC7A9, SLC3A1, SLC7A6 and 1 moreextracellular space, cytosol
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
- solute carrier organic anion transporter (cholate)
Catalysed by GLYATL2, GSS, SLCO1A2, SLCO1B3cytosol, extracellular spaceOne of 3 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- glycine:oxygen oxidoreductase (deaminating)
- glycolate:NADP+ oxidoreductase
Catalysed by GLYATL2, DAO, GRHPRperoxisome, cytosolOne of 3 routes
- (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
- transport of cysteine and glycine (cytosol to extracellular)
- L-cysteine hydrogen-sulfide-lyase (deaminating
Catalysed by GLYATL2, SLC3A2, SLC7A5, SLC7A8 and 1 moreextracellular space, cytosolOne of 3 routes