L-tyrosine

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. leukotriene C4 hydrolysis

Catalysed by AADATcytosol

1. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine
2. transport of asparagine and phenylalanine (cytosol to extracellular)

Catalysed by PAH, SLC7A5extracellular space, cytosolOne of 9 routes

1. L-tyrosine(out) + L-aspartate(in) = L-tyrosine(in) + L-aspartate(out)
2. N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)

Catalysed by SLC7A13, AGAinner side of the membrane, outer side of the membrane

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. N(omega),N(omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine

Catalysed by AADAT, AGXT2One of 2 routes

1. L-tyrosine(out) + L-aspartate(in) = L-tyrosine(in) + L-aspartate(out)
2. 1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)

Catalysed by SLC7A13, PAICSinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)

Catalysed by AADAT, GLYATL2One of 2 routes

1. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa
2. L-dopa + H(+) = dopamine + CO2

Catalysed by TH, DDC

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. Hippurate (Benzoylglycinate) Formation

Catalysed by AADATmitochondrial matrixOne of 2 routes

1. L-tyrosine(out) + L-aspartate(in) = L-tyrosine(in) + L-aspartate(out)
2. transport of 3-sulfinoalanine and aspartate (cytosol to mitochondria)

Catalysed by SLC7A13, SLC25A12, SLC25A13inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 4 routes

1. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine
2. 1-O-(1,2-saturated-alkyl)-sn-glycerol + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + O2 = a 1-(1-hydroxyalkyl)-sn-glycerol + (6R)-L-erythro-6,7-dihydrobiopterin + H2O

Catalysed by PAH, AGMO

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine

Catalysed by AADAT, AGXT2

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. Glycodeoxycholate amidohydrolase

Catalysed by AADATcytosolOne of 2 routes

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)

Catalysed by AADAT, GLYATL2

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)

Catalysed by AADAT, BAAT

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

Catalysed by AADAT, BAAT

1. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
2. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)

Catalysed by AADAT, BAAT

1. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa
2. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin
3. beta-carboline hydrolysis

Catalysed by TH, TPH1, TPH2cytosol

1. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine
2. Transport of L-Phenylalanine by Atb0 Transporter
3. Carnitine Transport by Atb0