L-alanine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

1,017 compounds within 3 steps: 50 in 1, 377 in 2, 590 in 3

Two steps

beta-carbolineReach from here →
1. transport of alanine and tryptophan (cytosol to extracellular)
2. beta-carboline hydrolysis
Catalysed by SLC7A5extracellular space, cytosol
(S)-carnitineReach from here →
1. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
2. Carnitine O-Palmitoyltransferase
Catalysed by CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 245 routes
2-hydroxybutyric acidReach from here →
1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
2. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)
Catalysed by AGXT2, SLC16A4, SLC16A5, SLC16A3 and 3 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes
3-methyl-2-oxobutanoateReach from here →
1. transport of alanine and valine (cytosol to extracellular)
2. L-Valine:2-oxoglutarate aminotransferase
Catalysed by SLC7A5, BCAT2extracellular space, cytosol, mitochondrial matrixOne of 3 routes
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphateReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)
Catalysed by MOCOS, MOCS1
AReach from here →
1. transport of alanine and cysteine (cytosol to extracellular)
2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by SLC7A5, MOCOSextracellular space, cytosolOne of 72 routes
glycoursodeoxycholateReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. glycine to glycoursodeoxycholate conversion
Catalysed by AGXT, AGXT2mitochondrial matrix, cytosolOne of 2 routes
(18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O
Catalysed by MOCOS, PTGS2
(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O
Catalysed by MOCOS, PTGS2
prostaglandin H3Reach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. prostaglandin G3 + AH2 = prostaglandin H3 + A + H2O
Catalysed by MOCOS, PTGS2
13-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. (9Z,12Z)-octadecadienoate + AH2 + O2 = 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O
Catalysed by MOCOS, PTGS2
9-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. (9Z,12Z)-octadecadienoate + AH2 + O2 = 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by MOCOS, PTGS2
N-(9Z-octadecenoyl)glycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. (9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL3, GLYATL2mitochondrial matrix
N-(9Z-octadecenoyl)-L-phenylalanineReach from here →
1. transport of alanine and phenylalanine (cytosol to extracellular)
2. L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O
Catalysed by SLC7A5, PM20D1extracellular space, cytosol
N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanineReach from here →
1. transport of alanine and phenylalanine (cytosol to extracellular)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine + H2O
Catalysed by SLC7A5, PM20D1extracellular space, cytosol
N-(9Z-octadecenoyl)-L-leucineReach from here →
1. transport of alanine and leucine (cytosol to extracellular)
2. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
Catalysed by SLC7A5, PM20D1extracellular space, cytosol
N-octadecanoylglycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. octadecanoyl-CoA + glycine = N-octadecanoylglycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix
N-(9Z-hexadecenoyl)-glycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. (9Z)-hexadecenoyl-CoA + glycine = N-(9Z-hexadecenoyl)-glycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix
(13R)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. (9Z,12Z)-octadecadienoate + AH2 + O2 = (13R)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O
Catalysed by MOCOS, PTGS1, PTGS2
acetoacetateReach from here →
1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)
Catalysed by AGXT2mitochondrial matrix, cytosolOne of 4 routes
2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O
Catalysed by MOCOS, PTGS2
2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O
Catalysed by MOCOS, PTGS2
2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O
Catalysed by MOCOS, PTGS2
2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamineReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine + A + H2O
Catalysed by MOCOS, PTGS2
2-(prostaglandin H2)-sn-glycero-3-phosphocholineReach from here →
1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. 2-(prostaglandin G2)-sn-glycero-3-phosphocholine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphocholine + A + H2O
Catalysed by MOCOS, PTGS2
N-(4-oxoglutaryl)-L-cysteinylglycineReach from here →
1. gamma-glutamyltransferase (alanine)
2. N-(4-oxoglutaryl)-L-cysteinylglycine + H2O = L-cysteinylglycine + 2-oxoglutarate
Catalysed by GGTLC3, GGT1, GGT5, GGTLC2 and 3 morecytosol
N-hexadecanoylglycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. hexadecanoyl-CoA + glycine = N-hexadecanoylglycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL3mitochondrial matrix
N-dodecanoylglycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. dodecanoyl-CoA + glycine = N-dodecanoylglycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix
N-decanoylglycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. decanoyl-CoA + glycine = N-decanoylglycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix
N-octanoylglycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix
D-histidineReach from here →
1. transport of alanine and ornithine (cytosol to extracellular)
2. D-histidine(in) + L-ornithine(out) + H(+)(in) = D-histidine(out) + L-ornithine(in) + H(+)(out)
Catalysed by SLC7A6, SLC25A2extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
L-homoarginineReach from here →
1. transport of alanine and arginine (cytosol to extracellular)
2. L-homoarginine(in) + L-arginine(out) = L-homoarginine(out) + L-arginine(in)
Catalysed by SLC7A6, SLC25A29extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes
L-homocarnosineReach from here →
1. transport of alanine and histidine (cytosol to extracellular)
2. Formation of homocarnosine
Catalysed by SLC7A6, CARNS1extracellular space, cytosol
N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. 5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)
Catalysed by AGXT, AGXT2, GARTmitochondrial matrix
L-cystine-bis-glycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
Catalysed by AGXT, AGXT2, DPEP1, DPEP2mitochondrial matrixOne of 3 routes
glycyldehydrophenylalanineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine
Catalysed by AGXT, AGXT2, DPEP1mitochondrial matrix
2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidineReach from here →
1. transport of alanine and glutamine (cytosol to extracellular)
2. N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)
Catalysed by SLC3A2, SLC7A5, SLC7A10, PFASextracellular space, cytosol
kinetensinReach from here →
1. transport of alanine and phenylalanine (cytosol to extracellular)
2. Chymase
Catalysed by SLC7A5, CMA1extracellular space, cytosolOne of 3 routes
an N-(fatty acyl)-glycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix
N-(9Z,12Z-octadecadienoyl)-glycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix
(7Z)-octadecenoyl-CoAReach from here →
1. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
2. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 3 routes
acetaldehydeReach from here →
1. transport of alanine and threonine (cytosol to extracellular)
2. L-threonine acetaldehyde-lyase (glycine-forming)
Catalysed by SLC7A5extracellular space, cytosolOne of 2 routes
CHEBI:15345Reach from here →
1. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
2. Acetoacetate:CoA ligase (AMP-forming)
Catalysed by AACSmitochondrial matrix, cytosolOne of 2 routes
cholineReach from here →
1. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
2. Acetyl-CoA:choline O-acetyltransferase
Catalysed by CHATmitochondrial matrix, nucleusOne of 2 routes
acetylpyruvateReach from here →
1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
2. acetylpyruvate + H2O = acetate + pyruvate + H(+)
Catalysed by AGXT2, FAHD1mitochondrial matrix
all-trans-retinoic acidReach from here →
1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
2. transport of pyruvate and retinoate (cytosol to extracellular)
Catalysed by AGXT2, SLC16A4, SLC16A5, SLC16A3 and 3 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes
4a-hydroxytetrahydrobiopterinReach from here →
1. transport of alanine and tryptophan (cytosol to extracellular)
2. L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase(5-hydroxylating)
Catalysed by SLC7A5, TPH1, TPH2extracellular space, cytosolOne of 3 routes
CHEBI:15380Reach from here →
1. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
2. 5-aminolevulinate synthase (2-amino-3-oxoadipate)
Catalysed by ALAS1, CPNE7mitochondrial matrixOne of 8 routes
CHEBI:15477Reach from here →
1. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
2. glycine N-acyltransferase (2-methylbutyryl-CoA)
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrixOne of 2 routes
2-methylcrotonoyl-CoAReach from here →
1. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
2. Production of Tiglylcarnitine
Catalysed by CPT1A, CPT1Bmitochondrial matrix, cytosolOne of 2 routes