Loading the page.
Proteins/UNIPROT:O95292
Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. Interacts with STARD3 in a FFAT motif phosphorylation dependent manner. Via interaction with WDR44 participates in neosynthesized protein export. Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation..
Function from UniProtKB (O95292), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
401 statements
401 statements · 5 reference databases · Subject: VAPB · Sources: gene ontology, Hetionet, Human-GEM, Reactome, WikiPathways · Rows fetched: 300
1 reaction
an N-acylsphing-4-eninean N-acylsphing-4-enine
Transported by CERT1 or VAPB or CSNK1G2 or PPM1L or PRKD1
Reaction pageReversibleBalance undeterminablecytosol, endoplasmic reticulum
Human-GEM MAR00730CC BY 4.0Reference data
3 names
Resolves to: VAPB