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Proteins/UNIPROT:Q5SGD2
Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6..
Function from UniProtKB (Q5SGD2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
43 statements
43 statements · 5 reference databases · Subject: PPM1L · Sources: Hetionet, Human-GEM, Reactome, UniProt, WikiPathways
3 reactions
an N-acylsphing-4-eninean N-acylsphing-4-enine
Transported by CERT1 or VAPB or CSNK1G2 or PPM1L or PRKD1
Reaction pageReversibleBalance undeterminablecytosol, endoplasmic reticulum
Human-GEM MAR00730CC BY 4.0Reference data
O-phospho-L-seryl-[protein]+waterL-seryl-[protein]+hydrogenphosphate
6 names
Resolves to: PPM1L
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:20629CC BY 4.0Reference data
O-phospho-L-threonyl-[protein]+waterL-threonyl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 59 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47004CC BY 4.0Reference data