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Proteins/UNIPROT:Q9Y5P4
Shelters ceramides inside its steroidogenic acute regulatory lipid transfer (START) domain and mediates their intracellular trafficking in a non-vesicular manner from the endoplasmic reticulum to the Golgi apparatus for conversion to sphingomyelin. Efficiently transfers ceramide molecules having long-chain fatty chains, but not those with very long acyl chains. Capable of transferring diacylglycerol, although with very low efficiency..
Function from UniProtKB (Q9Y5P4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
87 statements
87 statements · 6 reference databases · Subject: CERT1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Rhea, WikiPathways
15 reactions
an N-acylsphing-4-eninean N-acylsphing-4-enine
Transported by CERT1 or VAPB or CSNK1G2 or PPM1L or PRKD1
Reaction pageReversibleBalance undeterminablecytosol, endoplasmic reticulum
Human-GEM MAR00730CC BY 4.0Reference data
an N-acylsphing-4-eninean N-acylsphing-4-enine
Transported by CERT1
Reaction pageLeft to rightBalance undeterminablecytosol, Golgi apparatus
9 names
Resolves to: CERT1
D-glucosyl-N-acylsphingosineD-glucosyl-N-acylsphingosine
Transported by CERT1
Reaction pageLeft to rightBalance undeterminablecytosol, endoplasmic reticulum
Human-GEM MAR00768CC BY 4.0Reference data
D-glucosyl-N-acylsphingosineD-glucosyl-N-acylsphingosine
Transported by CERT1
Reaction pageReversibleBalance undeterminablecytosol, Golgi apparatus
Human-GEM MAR08146CC BY 4.0Reference data
N-hexadecanoylsphing-4-enineN-hexadecanoylsphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:45720CC BY 4.0Reference data
an N-acylsphing-4-eninean N-acylsphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:76987CC BY 4.0Reference data
N-tetradecanoylsphing-4-enineN-tetradecanoylsphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:85987CC BY 4.0Reference data
N-octadecanoylsphing-4-enineN-octadecanoylsphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:85991CC BY 4.0Reference data
N-eicosanoyl-sphing-4-enineN-eicosanoyl-sphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:85995CC BY 4.0Reference data
CHEBI:72966CHEBI:72966
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:85999CC BY 4.0Reference data
N-(15Z-tetracosenoyl)-sphing-4-enineN-(15Z-tetracosenoyl)-sphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:86003CC BY 4.0Reference data
N-hexadecanoylsphinganineN-hexadecanoylsphinganine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:86007CC BY 4.0Reference data