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Proteins/UNIPROT:Q9NW38
Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth..
Function from UniProtKB (Q9NW38), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
124 statements
124 statements · 3 reference databases · Subject: FANCL · Sources: Hetionet, Reactome, WikiPathways
1 reaction
5 names
Resolves to: FANCL
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data