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Proteins/UNIPROT:Q6UWE0
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. Bacterial recognition protein that defends the cytoplasm from invasive pathogens. Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy)..
Function from UniProtKB (Q6UWE0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
237 statements
237 statements · 4 reference databases · Subject: LRSAM1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 reaction
5 names
Resolves to: LRSAM1
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data