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Proteins/UNIPROT:P51003
Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus..
Function from UniProtKB (P51003), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
205 statements
205 statements · 4 reference databases · Subject: PAPOLA · Sources: Hetionet, Reactome, UniProt, WikiPathways
3 reactions
4 names
Resolves to: PAPOLA
Reaction pageLeft to rightBalance undeterminableEC 2.7.7.6, 2.7.7.19, 2.7.7.52nucleus
Human-GEM MAR07161CC BY 4.0Reference data
phosphate(3-)+MAM02847c0.18ADP+0.3CHEBI:17239+0.34GDP+0.18UDP
Catalysed by POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & PAPOLA & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & MTPAP & POLR3B & POLR1H & POLR3K & POLR3H or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & PAPOLA & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & PAPOLA & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & POLR3C & POLR1E & POLR3F & TUT1 & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & POLR3C & PAPOLG & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & POLR3C & PAPOLG & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & POLR3C & PAPOLG & POLR1E & POLR3F & TUT1 & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & TENT2 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & TENT2 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TENT2 & POLR3C & POLR1E & POLR3F & TUT1 & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & POLR3C & POLR1E & POLR3F & POLR1B & PAPOLB & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & POLR3C & POLR1E & POLR3F & POLR1B & PAPOLB & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & POLR3C & POLR1E & POLR3F & TUT1 & POLR1B & PAPOLB & POLR3E & and 12 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.7.7.8cytosol
Human-GEM MAR07162CC BY 4.0Reference data
RNA(n)+ATP(4-)RNA(n)-3'-adenine ribonucleotide+diphosphate(3-)
Catalysed by PAPOLA or TENT5C or TENT4A or TENT2 or TENT4B or TENT5D or TENT5B or TENT5A or PAPOLG or TUT1 or PAPOLB or MTPAP
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11332CC BY 4.0Reference data