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Proteins/UNIPROT:O94760
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation..
Function from UniProtKB (O94760), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
407 statements
407 statements · 8 reference databases · Subject: DDAH1 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
3 reactions
water+N(omega),N(omega)-dimethyl-L-arginineL-citrulline+dimethylamine
Catalysed by DDAH1
Reaction pageLeft to rightBalancedEC 3.5.3.18cytosol
Human-GEM MAR09513CC BY 4.0Reference data
N(omega),N(omega)-dimethyl-L-arginine+waterdimethylamine+L-citrulline
Catalysed by DDAH1
Reaction pageLeft to rightBalanced
6 names
Resolves to: DDAH1
N(omega)-methyl-L-arginine+waterL-citrulline+methylamine
Catalysed by DDAH1
Reaction pageLeft to rightBalanced
Rhea RHEA:25173CC BY 4.0Reference data