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Proteins/UNIPROT:O43747
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes..
Function from UniProtKB (O43747), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 rows
77 statements
77 statements · 5 reference databases · Subject: AP1G1 · Sources: gene ontology, Hetionet, Human-GEM, Reactome, WikiPathways
1 reaction
ATP+water+dodecanoateADP+proton+dodecanoate+phosphate(3-)
Transported by NAE1 or AP1G1 or CA5A
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR00190CC BY 4.0Reference data
8 names
Resolves to: AP1G1