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Proteins/UNIPROT:Q5H8A4
Catalytic subunit of the ethanolamine phosphate transferase 2 complex that transfers an ethanolamine phosphate (EtNP) from a phosphatidylethanolamine (PE) to the 6-OH position of the second alpha-1,6-linked mannose of a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol (also termed H7) intermediate to generate a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol (also termed H8) and participates in the eleventh step of the glycosylphosphatidylinositol-anchor biosynthesis..
Function from UniProtKB (Q5H8A4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
39 statements
39 statements · 6 reference databases · Subject: PIGG · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
7 reactions
MAM02461r+phosphatidylethanolaminea 1,2-diacyl-sn-glycerol+MAM03749r
Reaction pageLeft to rightBalance undeterminableendoplasmic reticulum
Human-GEM MAR01513CC BY 4.0Reference data
MAM02433r+phosphatidylethanolaminea 1,2-diacyl-sn-glycerol+MAM01781r
5 names
Resolves to: PIGG
Human-GEM MAR08393CC BY 4.0Reference data
MAM01781r+phosphatidylethanolaminea 1,2-diacyl-sn-glycerol+MAM01782r
Reaction pageLeft to rightBalance undeterminableendoplasmic reticulum
Human-GEM MAR08395CC BY 4.0Reference data
MAM02430r+phosphatidylethanolaminea 1,2-diacyl-sn-glycerol+MAM01779r
Catalysed by PIGF or PIGO or PIGG
Reaction pageLeft to rightBalance undeterminableendoplasmic reticulum
Human-GEM MAR08396CC BY 4.0Reference data
MAM01779r+phosphatidylethanolaminea 1,2-diacyl-sn-glycerol+MAM02020r
Reaction pageLeft to rightBalance undeterminableendoplasmic reticulum
Human-GEM MAR08398CC BY 4.0Reference data
MAM02432r+phosphatidylethanolaminea 1,2-diacyl-sn-glycerol+MAM02461r
Catalysed by PIGF or PIGO or PIGG
Reaction pageLeft to rightBalance undeterminableendoplasmic reticulum
Human-GEM MAR08401CC BY 4.0Reference data
a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol+a 1,2-diacyl-sn-glycero-3-phosphoethanolaminea 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol+a 1,2-diacyl-sn-glycerol
Catalysed by PIGG
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:61016CC BY 4.0Reference data