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Proteins/UNIPROT:P16233
Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones..
Function from UniProtKB (P16233), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
35 statements
35 statements · 7 reference databases · Subject: PNLIP · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea
14 reactions
a 1,2-diacyl-sn-glycerol+watera monoacylglycerol+MAM01807e
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3extracellular space
3 names
Resolves to: PNLIP
Human-GEM MAR00003CC BY 4.0Reference data
water+a triacylglycerola 1,2-diacyl-sn-glycerol+proton+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3cytosol
Human-GEM MAR00665CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+watera monoacylglycerol+proton+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3cytosol
Human-GEM MAR00667CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+watera monoacylglycerol+proton+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3cytosol
Human-GEM MAR00668CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+watera monoacylglycerol+proton+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3cytosol
Human-GEM MAR00669CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+watera monoacylglycerol+proton+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3cytosol
Human-GEM MAR00670CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+watera monoacylglycerol+proton+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3cytosol
Human-GEM MAR00671CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+watera monoacylglycerol+proton+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or DAGLB or LIPC or CEL or PNLIP or PNPLA2 or LIPF and 3 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.3cytosol
Human-GEM MAR00672CC BY 4.0Reference data
water+an all-trans-retinyl esterproton+all-trans-retinol+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or RBP4 or CES5A or DAGLB or LIPC or CEL or CES3 and 8 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.1, 3.1.1.3cytosol
Human-GEM MAR06636CC BY 4.0Reference data
a triacylglycerol+watera diacylglycerol+a fatty acid+hydron
Catalysed by DDHD2 or LPL or LIPF or ABHD2 or LIPC or PNLIP or CEL or AADAC or PNPLA4 or PNLIPRP2 or LIPE or PNLIPRP3 and 7 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12044CC BY 4.0Reference data
all-trans-retinyl hexadecanoate+waterall-trans-retinol+hexadecanoate+hydron
Catalysed by PNLIP or PNPLA4 or LIPE
Reaction pageLeft to rightBalanced
Rhea RHEA:13933CC BY 4.0Reference data
1,2-di-(9Z-octadecenoyl)-glycerol+water(9Z-octadecenoyl)-glycerol+(9Z)-octadecenoate+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:38455CC BY 4.0Reference data