Compound
CHEBI:12947
An N-acyl-D-galactosylsphingosine in which the anomeric configuration of the galactosyl residue is β; sphingosine substituted at the O-1 position by a β-D-galactosyl group and at the N-2 position by an acyl group.
Definition from ChEBI (CHEBI:12947), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
16 entities
16 entities reached.
0 reported hops16 assembled from the scaffold
- B4GALT1ProteinUNIPROT:P15291substrate ofInferred only84 paths42 endpoints
- B4GALT6ProteinUNIPROT:Q9UBX8substrate ofInferred only38 paths19 endpoints
- B4GALT5ProteinUNIPROT:O43286substrate ofInferred only36 paths18 endpoints
- B4GALT3ProteinUNIPROT:O60512substrate ofInferred only30 paths15 endpoints
- B4GALT4ProteinUNIPROT:O60513substrate ofInferred only28 paths14 endpoints
- B4GALT2ProteinUNIPROT:O60909substrate ofInferred only28 paths14 endpoints
- B4GALT7ProteinUNIPROT:Q9UBV7substrate ofInferred only24 paths12 endpoints
- GAL3ST1ProteinUNIPROT:Q99999substrate ofInferred only18 paths9 endpoints
- B3GALT1ProteinUNIPROT:Q9Y5Z6substrate ofInferred only18 paths9 endpoints
- B3GALT2ProteinUNIPROT:O43825substrate ofInferred only16 paths8 endpoints
- GALCProteinUNIPROT:P54803substrate ofInferred only16 paths8 endpoints
- POMGNT1ProteinUNIPROT:Q8WZA1substrate ofInferred only13 paths13 endpoints
What the reference databases state
Statements
55 statements
55 statements · 1 reference database · Subject: CHEBI:12947 · Sources: Human-GEM
- CHEBI:12947 is converted to an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enineCompoundHuman-GEM MAR00792Inferred only
- CHEBI:12947 is a substrate of A4GNTProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of A4GNTProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of ALG1L2ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of ALG1L2ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B3GALT1ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B3GALT1ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B3GALT2ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B3GALT2ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B3GALT5ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B3GALT5ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B3GLCTProteinHuman-GEM MAR00924Inferred only
Show the remaining 43
- CHEBI:12947 is a substrate of B3GNT7ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B3GNT9ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B3GNT9ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALNT2ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALNT2ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALNT4ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT1ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALT1ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT2ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT2ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALT3ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALT3ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT4ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT4ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALT5ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT5ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALT6ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of B4GALT6ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT7ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of B4GALT7ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of FUT4ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of GAL3ST1ProteinHuman-GEM MAR00792Inferred only
- CHEBI:12947 is a substrate of GAL3ST1ProteinHuman-GEM MAR08206Inferred only
- CHEBI:12947 is a substrate of GALCProteinHuman-GEM MAR08210Inferred only
- CHEBI:12947 is a substrate of GALCProteinHuman-GEM MAR00793Inferred only
- CHEBI:12947 is a substrate of GALNT7ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of GBGT1ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of GBGT1ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of GCNT7ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of GCNT7ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of GLT6D1ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of GLT6D1ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of GLT8D1ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of GLT8D1ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of GLT8D2ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of GLT8D2ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of MGAT5BProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of PIGZProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of POFUT3ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of POFUT4ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of POFUT4ProteinHuman-GEM MAR00924Inferred only
- CHEBI:12947 is a substrate of POMGNT1ProteinHuman-GEM MAR00925Inferred only
- CHEBI:12947 is a substrate of STT3BProteinHuman-GEM MAR00925Inferred only
Reactions
20 reactions
water+an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enineCHEBI:12947+proton+sulfate
Catalysed by ARSD or ARSA or ARSL
Reaction pageLeft to rightBalance undeterminableEC 3.1.6.8GO:0005764
Human-GEM MAR00790CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005764
Human-GEM MAR00791CC BY 4.0Reference data
CHEBI:12947+3'-phospho-5'-adenylyl sulfateproton+adenosine 3',5'-bismonophosphate+an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine
Catalysed by GAL3ST1
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.11GO:0005764
Human-GEM MAR00792CC BY 4.0Reference data
CHEBI:12947+wateran N-acylsphing-4-enine+D-glucose
Catalysed by GALC
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.46GO:0005764
Human-GEM MAR00793CC BY 4.0Reference data
water+a ganglioside GM4 (d18:1(4E))CHEBI:12947+proton+N-acetyl-beta-neuraminic acid
Catalysed by NEU2 or NEU3 or NEU4 or NEU1
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.18GO:0005764
Human-GEM MAR00834CC BY 4.0Reference data
an N-acylsphing-4-enine+CHEBI:67119CHEBI:12947+proton+UDP
Catalysed by UGT8
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.47GO:0005829
Human-GEM MAR00919CC BY 4.0Reference data
an N-acylsphing-4-enine+CHEBI:67119CHEBI:12947+proton+UDP
Catalysed by UGT8
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.47GO:0005794
Human-GEM MAR00920CC BY 4.0Reference data
an N-acylsphing-4-enine+CHEBI:67119CHEBI:12947+proton+UDP
Catalysed by UGT8
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.47GO:0005783
Human-GEM MAR00921CC BY 4.0Reference data
CHEBI:12947+CHEBI:67119MAM01694c+proton+UDP
Catalysed by GLT8D1 or B4GALT7 or B4GALT1 or B4GALT2 or A4GNT or B4GALT6 or GLT8D2 or B4GALT4 or GCNT7 or GBGT1 or B4GALT5 or B4GALT3 and 10 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-GO:0005829
Human-GEM MAR00924CC BY 4.0Reference data
CHEBI:12947+CHEBI:67119MAM01694g+proton+UDP
Catalysed by GLT8D1 or B4GALT7 or POMGNT1 or B4GALT1 or GALNT7 or B4GALT2 or A4GNT or B4GALT6 or PIGZ or GLT8D2 or B4GALT4 or GCNT7 and 16 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-GO:0005794
Human-GEM MAR00925CC BY 4.0Reference data
an N-acylsphing-4-enine+CHEBI:67119CHEBI:12947+proton+UDP
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.47GO:0005615
Human-GEM MAR03248CC BY 4.0Reference data
an N-acylsphing-4-enine+CHEBI:67119CHEBI:12947+proton+UDP
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.47GO:0005634
Human-GEM MAR03249CC BY 4.0Reference data