Compound
N-hexadecanoylsphinganine
A dihydroceramide in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl).
Definition from ChEBI (CHEBI:67042), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C34H69NO3
- Mass
- 539.93 g/mol
- Charge
- 0
- InChIKey
- GCGTXOVNNFGTPQ-JHOUSYSJSA-N
- SMILES
- CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- CERT1ProteinUNIPROT:Q9Y5P4transported byInferred only47 paths47 endpoints
- SGMS2ProteinUNIPROT:Q8NHU3substrate ofInferred only20 paths10 endpoints
- SGMS1ProteinUNIPROT:Q86VZ5substrate ofInferred only10 paths10 endpoints
- ASAH2ProteinUNIPROT:Q9NR71substrate ofInferred only7 paths7 endpoints
- SAMD8ProteinUNIPROT:Q96LT4substrate ofInferred only4 paths4 endpoints
What the reference databases state
Chemical structure
- N-hexadecanoylsphinganine has the functional parent hexadecanoic acidCompoundChEBI CHEBI:67042Inferred only
- N-hexadecanoyl-sphinganine-1-phosphoethanolamine has the functional parent N-hexadecanoylsphinganineCompoundChEBI CHEBI:78654Inferred only
Statements
6 statements
6 statements · 1 reference database · Subject: N-hexadecanoylsphinganine · Sources: Rhea
- N-hexadecanoylsphinganine is a substrate of ASAH2ProteinRhea RHEA:43440Inferred only
- N-hexadecanoylsphinganine is a substrate of SAMD8ProteinRhea RHEA:42128Inferred only
- N-hexadecanoylsphinganine is a substrate of SGMS1ProteinRhea RHEA:41796Inferred only
- N-hexadecanoylsphinganine is a substrate of SGMS2ProteinRhea RHEA:41796Inferred only
- N-hexadecanoylsphinganine is a substrate of SGMS2ProteinRhea RHEA:42128Inferred only
- N-hexadecanoylsphinganine is transported by CERT1ProteinRhea RHEA:86007Inferred only
Reactions
7 reactions
sphinganine+hexadecanoyl-CoAN-hexadecanoylsphinganine+coenzyme A(4-)+hydron
Catalysed by CERS6 or CERS5 or CERS2
Reaction pageLeft to rightBalanced
Rhea RHEA:36539CC BY 4.0Reference data
N-hexadecanoylsphinganine+a 1,2-diacyl-sn-glycero-3-phosphocholineN-hexadecanoyl-sphinganine-1-phosphocholine+a 1,2-diacyl-sn-glycerol
Reaction pageReversibleBalance undeterminable
Rhea RHEA:41796CC BY 4.0Reference data
N-hexadecanoylsphinganine+a 1,2-diacyl-sn-glycero-3-phosphoethanolamineN-hexadecanoyl-sphinganine-1-phosphoethanolamine+a 1,2-diacyl-sn-glycerol
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42128CC BY 4.0Reference data
sphinganine+hexadecanoateN-hexadecanoylsphinganine+water
Catalysed by ASAH2
Reaction pageRight to leftBalanced
Rhea RHEA:43440CC BY 4.0Reference data
beta-D-galactosyl-(1<->1')-N-hexadecanoylsphinganine+waterbeta-D-galactose+N-hexadecanoylsphinganine
Catalysed by LCT
Reaction pageLeft to rightBalanced
Rhea RHEA:69707CC BY 4.0Reference data
beta-D-glucosyl-(1<->1')-N-hexadecanoylsphinganine+waterN-hexadecanoylsphinganine+beta-D-glucose
Catalysed by LCT
Reaction pageLeft to rightBalanced
Rhea RHEA:69711CC BY 4.0Reference data
N-hexadecanoylsphinganineN-hexadecanoylsphinganine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:86007CC BY 4.0Reference data
Where it reaches
8 systems, 19 regions, 42 tissues, 42 transporter routes — routes, not measurements: transporters known to carry N-hexadecanoylsphinganine are expressed there, and no source reports it arriving.
Loading the model…
Other names
14 names
Resolves to: N-hexadecanoylsphinganine
- Also called
- C16DH CerCer 34:0;O2Cer(d18:0/16:0)Cer[NdS]DHC-A 18:0/16:0N-(hexadecanoyl)-dihydroceramideN-(hexadecanoyl)-sphinganineN-(palmitoyl)-dihydroceramideN-hexadecanoyldihydroceramideN-hexadecanoyldihydrosphingosineN-palmitoyldihydroceramideN-palmitoyldihydrosphingosineN-palmitoylsphinganine
- Systematic name
- N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]hexadecanamide