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Proteins/UNIPROT:P35270
Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
Function from UniProtKB (P35270), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
595 statements
595 statements · 6 reference databases · Subject: SPR · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
6 reactions
MAM01170c+2proton+2NADPH(4-)2NADP(3-)+5,6,7,8-tetrahydrobiopterin
Catalysed by SPR
Reaction pageReversibleBalancedEC 1.1.1.153cytosol
Human-GEM MAR04165CC BY 4.0Reference data
MAM01170c+proton+NADPH(4-)MAM01164c+NADP(3-)
Catalysed by SPR
Human-GEM MAR04166CC BY 4.0Reference data
MAM01164c+proton+NADPH(4-)NADP(3-)+5,6,7,8-tetrahydrobiopterin
Catalysed by SPR
Reaction pageLeft to rightBalancedEC 1.1.1.153cytosol
Human-GEM MAR04167CC BY 4.0Reference data
MAM01170n+2proton+2NADPH(4-)2NADP(3-)+5,6,7,8-tetrahydrobiopterin
Catalysed by SPR
Reaction pageLeft to rightBalancedEC 1.1.1.153nucleus
Human-GEM MAR08739CC BY 4.0Reference data
L-erythro-7,8-dihydrobiopterin+NADP(3-)L-sepiapterin+NADPH(4-)+hydron
Catalysed by SPR
Reaction pageRight to leftBalanced
Rhea RHEA:18953CC BY 4.0Reference data
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin+2NADP(3-)6-pyruvoyl-5,6,7,8-tetrahydropterin+2NADPH(4-)+2hydron
Catalysed by SPR
Reaction pageRight to leftBalanced
Rhea RHEA:32627CC BY 4.0Reference data