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Proteins/UNIPROT:Q96DU7
Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity)..
Function from UniProtKB (Q96DU7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
52 statements
52 statements · 5 reference databases · Subject: ITPKC · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
2 reactions
ATP+1D-myo-inositol 1,4,5-trisphosphateMAM00522c+ADP+proton
Catalysed by ITPKC or ITPKA or ITPKB
Reaction pageLeft to rightBalancedEC 2.7.1.127cytosol
Human-GEM MAR06563CC BY 4.0Reference data
1D-myo-inositol 1,4,5-trisphosphate+ATP(4-)CHEBI:57895+ADP(3-)+hydron
Catalysed by
5 names
Resolves to: ITPKC
Reaction pageLeft to rightBalanced
Rhea RHEA:11020CC BY 4.0Reference data