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Proteins/UNIPROT:P50748
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex..
Function from UniProtKB (P50748), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
50 statements
50 statements · 3 reference databases · Subject: KNTC1 · Sources: gene ontology, Hetionet, Reactome
5 names
Resolves to: KNTC1