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Proteins/UNIPROT:Q08334
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state..
Function from UniProtKB (Q08334), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
71 statements
71 statements · 4 reference databases · Subject: IL10RB · Sources: gene ontology, Hetionet, Reactome, WikiPathways
13 names
Resolves to: IL10RB