Proteins/UNIPROT:P11532

DMD

ProteinUNIPROT:P11532

Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission..

Function from UniProtKB (P11532), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

7 rows

Becker muscular dystrophy has a germline basis in DMDDiseaseGenCC HGNC:2928|MONDO:0010311Inferred only
dilated cardiomyopathy 3B has a germline basis in DMDDiseaseGenCC HGNC:2928|MONDO:0010542Inferred only
Duchenne muscular dystrophy has a germline basis in DMDDiseaseGenCC HGNC:2928|MONDO:0010679Inferred only
familial isolated dilated cardiomyopathy has a germline basis in DMDDiseaseGenCC HGNC:2928|MONDO:0700335Inferred only
non-syndromic X-linked intellectual disability has a germline basis in DMDDiseaseGenCC HGNC:2928|MONDO:0019181Inferred only
progressive muscular dystrophy has a germline basis in DMDDiseaseGenCC HGNC:2928|MONDO:0016106Inferred only
symptomatic form of muscular dystrophy of Duchenne and Becker in female carriers has a germline basis in DMDDiseaseGenCC HGNC:2928|MONDO:0016097Inferred only

Statements

197 statements

197 statements · 4 reference databases · Subject: DMD · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

ASB4 covaries with DMDProteinHetionet hetionet:covaries:1756-51666Inferred only
ASPDH covaries with DMDProteinHetionet hetionet:covaries:1756-554235Inferred only
C11orf96 covaries with DMDProteinHetionet hetionet:covaries:1756-387763Inferred only
DMD covaries with C1QL4ProteinHetionet hetionet:covaries:1756-338761Inferred only
DMD covaries with CASD1ProteinHetionet hetionet:covaries:1756-64921Inferred only
DMD covaries with CCDC54ProteinHetionet hetionet:covaries:1756-84692Inferred only
DMD covaries with CEP85ProteinHetionet hetionet:covaries:1756-64793Inferred only
CLEC2L covaries with DMDProteinHetionet hetionet:covaries:154790-1756Inferred only
DMD covaries with CNKSR2ProteinHetionet hetionet:covaries:1756-22866Inferred only
DMD covaries with CORO1AProteinHetionet hetionet:covaries:11151-1756Inferred only
DMD covaries with COX6A2ProteinHetionet hetionet:covaries:1339-1756Inferred only
CUL7 covaries with DMDProteinHetionet hetionet:covaries:1756-9820Inferred only

Show the remaining 185

DMD covaries with CYP46A1ProteinHetionet hetionet:covaries:10858-1756Inferred only
DCAF8 covaries with DMDProteinHetionet hetionet:covaries:1756-50717Inferred only
DMD covaries with DHX30ProteinHetionet hetionet:covaries:1756-22907Inferred only
DMD covaries with DNAJC18ProteinHetionet hetionet:covaries:1756-202052Inferred only
DMD covaries with DTX3ProteinHetionet hetionet:covaries:1756-196403Inferred only
DMD covaries with DVL2ProteinHetionet hetionet:covaries:1756-1856Inferred only
DMD covaries with EHD2ProteinHetionet hetionet:covaries:1756-30846Inferred only
DMD covaries with EXOC3L1ProteinHetionet hetionet:covaries:1756-283849Inferred only
DMD covaries with FAM171BProteinHetionet hetionet:covaries:165215-1756Inferred only
DMD covaries with FBXO21ProteinHetionet hetionet:covaries:1756-23014Inferred only
DMD covaries with FEM1BProteinHetionet hetionet:covaries:10116-1756Inferred only
DMD covaries with FRS2ProteinHetionet hetionet:covaries:10818-1756Inferred only
DMD covaries with GEMIN4ProteinHetionet hetionet:covaries:1756-50628Inferred only
DMD covaries with GOLGB1ProteinHetionet hetionet:covaries:1756-2804Inferred only
DMD covaries with H2BC4; H2BC6; H2BC7; H2BC8; H2BC10ProteinHetionet hetionet:covaries:1756-8347Inferred only
DMD covaries with HOXA1ProteinHetionet hetionet:covaries:1756-3198Inferred only
DMD covaries with HOXC10ProteinHetionet hetionet:covaries:1756-3226Inferred only
DMD covaries with IGIPProteinHetionet hetionet:covaries:1756-492311Inferred only
DMD covaries with IRX2ProteinHetionet hetionet:covaries:153572-1756Inferred only
DMD covaries with ISYNA1ProteinHetionet hetionet:covaries:1756-51477Inferred only
DMD covaries with KANSL1ProteinHetionet hetionet:covaries:1756-284058Inferred only
DMD covaries with KBTBD3ProteinHetionet hetionet:covaries:143879-1756Inferred only
DMD covaries with KCTD11ProteinHetionet hetionet:covaries:147040-1756Inferred only
DMD covaries with KCTD19ProteinHetionet hetionet:covaries:146212-1756Inferred only
DMD covaries with KLHL22ProteinHetionet hetionet:covaries:1756-84861Inferred only
DMD covaries with LHFPL3ProteinHetionet hetionet:covaries:1756-375612Inferred only
DMD covaries with LRRC36ProteinHetionet hetionet:covaries:1756-55282Inferred only
DMD covaries with LZTS3ProteinHetionet hetionet:covaries:1756-9762Inferred only
DMD covaries with MBD5ProteinHetionet hetionet:covaries:1756-55777Inferred only
MGA covaries with DMDProteinHetionet hetionet:covaries:1756-23269Inferred only
DMD covaries with MSH6ProteinHetionet hetionet:covaries:1756-2956Inferred only
DMD covaries with MSL1ProteinHetionet hetionet:covaries:1756-339287Inferred only
DMD covaries with MTDHProteinHetionet hetionet:covaries:1756-92140Inferred only
MYO1B covaries with DMDProteinHetionet hetionet:covaries:1756-4430Inferred only
DMD covaries with NCOA1ProteinHetionet hetionet:covaries:1756-8648Inferred only
DMD covaries with NCOA6ProteinHetionet hetionet:covaries:1756-23054Inferred only
DMD covaries with NDNProteinHetionet hetionet:covaries:1756-4692Inferred only
DMD covaries with NF2ProteinHetionet hetionet:covaries:1756-4771Inferred only
DMD covaries with NHERF2ProteinHetionet hetionet:covaries:1756-9351Inferred only
DMD covaries with NSG2ProteinHetionet hetionet:covaries:1756-51617Inferred only
DMD covaries with ODF1ProteinHetionet hetionet:covaries:1756-4956Inferred only
DMD covaries with OMGProteinHetionet hetionet:covaries:1756-4974Inferred only
OPN1LW covaries with DMDProteinHetionet hetionet:covaries:1756-5956Inferred only
DMD covaries with PAQR9ProteinHetionet hetionet:covaries:1756-344838Inferred only
DMD covaries with PCF11ProteinHetionet hetionet:covaries:1756-51585Inferred only
DMD covaries with PCP2ProteinHetionet hetionet:covaries:126006-1756Inferred only
DMD covaries with PDCD11ProteinHetionet hetionet:covaries:1756-22984Inferred only
PDE4DIP covaries with DMDProteinHetionet hetionet:covaries:1756-9659Inferred only
DMD covaries with PHF20ProteinHetionet hetionet:covaries:1756-51230Inferred only
DMD covaries with PIM1ProteinHetionet hetionet:covaries:1756-5292Inferred only
DMD covaries with PPP1R9BProteinHetionet hetionet:covaries:1756-84687Inferred only
DMD covaries with PTPRFProteinHetionet hetionet:covaries:1756-5792Inferred only
DMD covaries with RAB24ProteinHetionet hetionet:covaries:1756-53917Inferred only
DMD covaries with RLFProteinHetionet hetionet:covaries:1756-6018Inferred only
DMD covaries with RNF180ProteinHetionet hetionet:covaries:1756-285671Inferred only
DMD covaries with S100PBPProteinHetionet hetionet:covaries:1756-64766Inferred only
DMD covaries with SBSPONProteinHetionet hetionet:covaries:157869-1756Inferred only
SELENOK covaries with DMDProteinHetionet hetionet:covaries:1756-58515Inferred only
SERF2 covaries with DMDProteinHetionet hetionet:covaries:10169-1756Inferred only
DMD covaries with SIL1ProteinHetionet hetionet:covaries:1756-64374Inferred only
DMD covaries with SP7ProteinHetionet hetionet:covaries:121340-1756Inferred only
SPRY3 covaries with DMDProteinHetionet hetionet:covaries:10251-1756Inferred only
DMD covaries with SRBD1ProteinHetionet hetionet:covaries:1756-55133Inferred only
DMD covaries with STAT4ProteinHetionet hetionet:covaries:1756-6775Inferred only
DMD covaries with SYT5ProteinHetionet hetionet:covaries:1756-6861Inferred only
TAF1 covaries with DMDProteinHetionet hetionet:covaries:1756-6872Inferred only
DMD covaries with TAGLN3ProteinHetionet hetionet:covaries:1756-29114Inferred only
DMD covaries with TBKBP1ProteinHetionet hetionet:covaries:1756-9755Inferred only
DMD covaries with TBX21ProteinHetionet hetionet:covaries:1756-30009Inferred only
TGIF2 covaries with DMDProteinHetionet hetionet:covaries:1756-60436Inferred only
DMD covaries with THAP12ProteinHetionet hetionet:covaries:1756-5612Inferred only
DMD covaries with TRAF4ProteinHetionet hetionet:covaries:1756-9618Inferred only
DMD covaries with TRIM17ProteinHetionet hetionet:covaries:1756-51127Inferred only
TRPC5 covaries with DMDProteinHetionet hetionet:covaries:1756-7224Inferred only
TSC22D3 covaries with DMDProteinHetionet hetionet:covaries:1756-1831Inferred only
DMD covaries with TSC22D4ProteinHetionet hetionet:covaries:1756-81628Inferred only
DMD covaries with TSSK6ProteinHetionet hetionet:covaries:1756-83983Inferred only
DMD covaries with UFSP1ProteinHetionet hetionet:covaries:1756-402682Inferred only
USP24 covaries with DMDProteinHetionet hetionet:covaries:1756-23358Inferred only
DMD covaries with VEGFBProteinHetionet hetionet:covaries:1756-7423Inferred only
DMD covaries with VPS28ProteinHetionet hetionet:covaries:1756-51160Inferred only
VPS53 covaries with DMDProteinHetionet hetionet:covaries:1756-55275Inferred only
DMD covaries with WNT7BProteinHetionet hetionet:covaries:1756-7477Inferred only
ZNF286A covaries with DMDProteinHetionet hetionet:covaries:1756-57335Inferred only
ZNF300 covaries with DMDProteinHetionet hetionet:covaries:1756-91975Inferred only
ZNF331 covaries with DMDProteinHetionet hetionet:covaries:1756-55422Inferred only
DMD covaries with ZNF502ProteinHetionet hetionet:covaries:1756-91392Inferred only
DMD covaries with ZNF662ProteinHetionet hetionet:covaries:1756-389114Inferred only
DMD covaries with ZNF689ProteinHetionet hetionet:covaries:115509-1756Inferred only
ACTA1 interacts with DMDProteinHetionet hetionet:interacts:1756-58Inferred only
ACTC1 interacts with DMDProteinHetionet hetionet:interacts:1756-70Inferred only
ANK2 interacts with DMDProteinHetionet hetionet:interacts:1756-287Inferred only
APP interacts with DMDProteinHetionet hetionet:interacts:1756-351Inferred only
ARRB1 interacts with DMDProteinHetionet hetionet:interacts:1756-408Inferred only
DMD interacts with CADPSProteinHetionet hetionet:interacts:1756-8618Inferred only
DMD interacts with CADPS2ProteinHetionet hetionet:interacts:1756-93664Inferred only
CDC25A interacts with DMDProteinHetionet hetionet:interacts:1756-993Inferred only
DAG1 interacts with DMDProteinHetionet hetionet:interacts:1605-1756Inferred only
DMD interacts with DGKZProteinHetionet hetionet:interacts:1756-8525Inferred only
DMD interacts with DISC1ProteinHetionet hetionet:interacts:1756-27185Inferred only
DMD interacts with DTNAProteinHetionet hetionet:interacts:1756-1837Inferred only
DMD interacts with DTNBProteinHetionet hetionet:interacts:1756-1838Inferred only
FASLG interacts with DMDProteinHetionet hetionet:interacts:1756-356Inferred only
DMD interacts with IFT54ProteinHetionet hetionet:interacts:1756-26146Inferred only
DMD interacts with KCNJ12ProteinHetionet hetionet:interacts:1756-3768Inferred only
DMD interacts with KRT19ProteinHetionet hetionet:interacts:1756-3880Inferred only
DMD interacts with KRT8ProteinHetionet hetionet:interacts:1756-3856Inferred only
DMD interacts with MAP3K5ProteinHetionet hetionet:interacts:1756-4217Inferred only
DMD interacts with PGM5ProteinHetionet hetionet:interacts:1756-5239Inferred only
DMD interacts with SGCZProteinHetionet hetionet:interacts:137868-1756Inferred only
DMD interacts with SNTA1ProteinHetionet hetionet:interacts:1756-6640Inferred only
DMD interacts with SNTB1ProteinHetionet hetionet:interacts:1756-6641Inferred only
DMD interacts with SNTB2ProteinHetionet hetionet:interacts:1756-6645Inferred only
DMD interacts with SNTG1ProteinHetionet hetionet:interacts:1756-54212Inferred only
DMD interacts with SNTG2ProteinHetionet hetionet:interacts:1756-54221Inferred only
DMD interacts with TERF2ProteinHetionet hetionet:interacts:1756-7014Inferred only
DMD interacts with UBCProteinHetionet hetionet:interacts:1756-7316Inferred only
DMD interacts with UTRNProteinHetionet hetionet:interacts:1756-7402Inferred only
DMD participates in 13q12 12 copy number variationPathwayWikiPathways WP5406Inferred only
DMD participates in Acute viral myocarditisPathwayWikiPathways WP4298Inferred only
DMD participates in Affected pathways in Duchenne muscular dystrophyPathwayWikiPathways WP5356Inferred only
DMD participates in Arrhythmogenic right ventricular cardiomyopathyPathwayWikiPathways WP2118Inferred only
DMD participates in Ectoderm differentiationPathwayWikiPathways WP2858Inferred only
DMD participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
DMD participates in Formation of the dystrophin-glycoprotein complex (DGC)PathwayReactome R-HSA-9913351Inferred only
DMD participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
DMD participates in Non-integrin membrane-ECM interactionsPathwayReactome R-HSA-3000171Inferred only
DMD participates in Striated Muscle ContractionPathwayReactome R-HSA-390522Inferred only
DMD participates in Striated muscle contraction pathwayPathwayWikiPathways WP383Inferred only
DMD regulates negative regulation of neuron differentiationBiological processgene ontology P11532|GO:0045665Inferred only
DMD regulates positive regulation of cell population proliferationBiological processgene ontology P11532|GO:0008284Inferred only
DMD regulates positive regulation of cell-matrix adhesionBiological processgene ontology P11532|GO:0001954Inferred only
DMD regulates positive regulation of neuron differentiationBiological processgene ontology P11532|GO:0045666Inferred only
DMD regulates positive regulation of neuron projection developmentBiological processgene ontology P11532|GO:0010976Inferred only
DMD regulates regulation of calcium ion transmembrane transportBiological processgene ontology P11532|GO:1903169Inferred only
DMD regulates regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionBiological processgene ontology P11532|GO:0010881Inferred only
DMD regulates regulation of cellular response to growth factor stimulusBiological processgene ontology P11532|GO:0090287Inferred only
DMD regulates regulation of heart rateBiological processgene ontology P11532|GO:0002027Inferred only
DMD regulates regulation of muscle system processBiological processgene ontology P11532|GO:0090257Inferred only
DMD regulates regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumBiological processgene ontology P11532|GO:0010880Inferred only
DMD regulates regulation of skeletal muscle contractionBiological processgene ontology P11532|GO:0014819Inferred only
DMD regulates regulation of skeletal muscle contraction by regulation of release of sequestered calcium ionBiological processgene ontology P11532|GO:0014809Inferred only
DMD regulates regulation of sodium ion transmembrane transportBiological processgene ontology P11532|GO:1902305Inferred only
DMD increases the expression of ABCC5ProteinHetionet hetionet:regulates:1756-10057Inferred only
DMD increases the expression of ACOT8ProteinHetionet hetionet:regulates:1756-10005Inferred only
DMD increases the expression of AKAP8LProteinHetionet hetionet:regulates:1756-26993Inferred only
DMD increases the expression of ALDOCProteinHetionet hetionet:regulates:1756-230Inferred only
DMD increases the expression of ANKZF1ProteinHetionet hetionet:regulates:1756-55139Inferred only
DMD decreases the expression of ANXA1ProteinHetionet hetionet:regulates:1756-301Inferred only
DMD increases the expression of ARFIP2ProteinHetionet hetionet:regulates:1756-23647Inferred only
DMD decreases the expression of ATF1ProteinHetionet hetionet:regulates:1756-466Inferred only
DMD decreases the expression of ATP6V1DProteinHetionet hetionet:regulates:1756-51382Inferred only
DMD increases the expression of BNIP3ProteinHetionet hetionet:regulates:1756-664Inferred only
DMD increases the expression of C2CD2LProteinHetionet hetionet:regulates:1756-9854Inferred only
DMD decreases the expression of CCNB1ProteinHetionet hetionet:regulates:1756-891Inferred only
DMD decreases the expression of CCND3ProteinHetionet hetionet:regulates:1756-896Inferred only
DMD decreases the expression of CDC20ProteinHetionet hetionet:regulates:1756-991Inferred only
DMD decreases the expression of CTSLProteinHetionet hetionet:regulates:1756-1514Inferred only
DMD increases the expression of DDX42ProteinHetionet hetionet:regulates:1756-11325Inferred only
DMD increases the expression of GARRE1ProteinHetionet hetionet:regulates:1756-9710Inferred only
DMD decreases the expression of HACD3ProteinHetionet hetionet:regulates:1756-51495Inferred only
DMD decreases the expression of ITGAEProteinHetionet hetionet:regulates:1756-3682Inferred only
DMD increases the expression of KDM5BProteinHetionet hetionet:regulates:1756-10765Inferred only
DMD decreases the expression of KRT18ProteinHetionet hetionet:regulates:1756-3875Inferred only
DMD decreases the expression of KRT8ProteinHetionet hetionet:regulates:1756-3856Inferred only
DMD increases the expression of MINDY1ProteinHetionet hetionet:regulates:1756-55793Inferred only
DMD decreases the expression of MYOFProteinHetionet hetionet:regulates:1756-26509Inferred only
DMD increases the expression of PFKLProteinHetionet hetionet:regulates:1756-5211Inferred only
DMD decreases the expression of PLEK2ProteinHetionet hetionet:regulates:1756-26499Inferred only
DMD decreases the expression of PLIN2ProteinHetionet hetionet:regulates:1756-123Inferred only
DMD decreases the expression of PPP2R5EProteinHetionet hetionet:regulates:1756-5529Inferred only
DMD decreases the expression of RPIAProteinHetionet hetionet:regulates:1756-22934Inferred only
DMD increases the expression of RRP8ProteinHetionet hetionet:regulates:1756-23378Inferred only
DMD increases the expression of SATB1ProteinHetionet hetionet:regulates:1756-6304Inferred only
DMD decreases the expression of SPRProteinHetionet hetionet:regulates:1756-6697Inferred only
DMD increases the expression of ST3GAL5ProteinHetionet hetionet:regulates:1756-8869Inferred only
DMD increases the expression of STXBP1ProteinHetionet hetionet:regulates:1756-6812Inferred only
DMD increases the expression of TM7SF2ProteinHetionet hetionet:regulates:1756-7108Inferred only
DMD decreases the expression of TMCO1ProteinHetionet hetionet:regulates:1756-54499Inferred only
DMD decreases the expression of TMEM109ProteinHetionet hetionet:regulates:1756-79073Inferred only
DMD decreases the expression of TNFRSF21ProteinHetionet hetionet:regulates:1756-27242Inferred only
DMD decreases the expression of TSPAN4ProteinHetionet hetionet:regulates:1756-7106Inferred only
DMD increases the expression of TSPAN8ProteinHetionet hetionet:regulates:1756-7103Inferred only
DMD increases the expression of VPS4AProteinHetionet hetionet:regulates:1756-27183Inferred only
DMD decreases the expression of YBX3ProteinHetionet hetionet:regulates:1756-8531Inferred only

Other names

1 name

Resolves to: DMD

Also called: Dystrophin

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