Compound

6-pyruvoyl-5,6,7,8-tetrahydropterin

A dyspropterin in which the stereocentre at position 6 has R-configuration.

Definition from ChEBI (CHEBI:136564), read 2026-09-23. CC BY 4.0.

CHEBI:136564ChEBI

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Structure

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A generated conformer of 6-pyruvoyl-5,6,7,8-tetrahydropterin — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C9H11N5O3
Mass: 237.219 g/mol
Charge: 0
InChIKey: WBJZXBUVECZHCE-SCSAIBSYSA-N
SMILES: [H][C@]1(C(=O)C(C)=O)CNc2nc(N)nc(=O)c2N1
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

3 statements

3 statements · 1 reference database · Subject: 6-pyruvoyl-5,6,7,8-tetrahydropterin · Sources: Rhea

Order

6-pyruvoyl-5,6,7,8-tetrahydropterin is converted to (6R)-L-erythro-5,6,7,8-tetrahydrobiopterinCompoundRhea RHEA:32627Inferred only
6-pyruvoyl-5,6,7,8-tetrahydropterin is a substrate of PTSProteinRhea RHEA:22048Inferred only
6-pyruvoyl-5,6,7,8-tetrahydropterin is a substrate of SPRProteinRhea RHEA:32627Inferred only

Reactions

7 reactions

CHEBI:27714+glutathione disulfide+water6-pyruvoyl-5,6,7,8-tetrahydropterin+2glutathione
Reaction pageDirection not assertedBalanced
Rhea RHEA:10720CC BY 4.0Reference data
CHEBI:136565+NADP(3-)6-pyruvoyl-5,6,7,8-tetrahydropterin+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:11772CC BY 4.0Reference data
7,8-dihydroneopterin 3'-triphosphate6-pyruvoyl-5,6,7,8-tetrahydropterin+triphosphate+hydron
Catalysed by PTS
Reaction pageDirection not assertedBalanced
Rhea RHEA:22048CC BY 4.0Reference data
CHEBI:136570+2NADP(3-)6-pyruvoyl-5,6,7,8-tetrahydropterin+2NADPH(4-)+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:24738CC BY 4.0Reference data
CHEBI:64241+2NADP(3-)6-pyruvoyl-5,6,7,8-tetrahydropterin+2NADPH(4-)+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:32623CC BY 4.0Reference data
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin+2NADP(3-)6-pyruvoyl-5,6,7,8-tetrahydropterin+2NADPH(4-)+2hydron
Catalysed by SPR
Reaction pageRight to leftBalanced
Rhea RHEA:32627CC BY 4.0Reference data
6-pyruvoyl-5,6,7,8-tetrahydropterin+waterCHEBI:61032+acetaldehyde+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:83627CC BY 4.0Reference data

Other names

1 name

Resolves to: 6-pyruvoyl-5,6,7,8-tetrahydropterin

Also called: (6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin