prostaglandin H2

1. prostaglandin-D synthase (prostaglandin H2)
2. 15-dehydro-prostaglandin D2 reduction

Catalysed by HPGDS, PTGDScytosolOne of 2 routes

1. transport of GSH and prostaglandin H2 (cytosol to extracellular)
2. Glutathione: 15-HPETE oxidoreductase

Catalysed by SLCO2A1, GPX5, GPX1, GPX2 and 6 moreextracellular space, cytosol

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of leukotriene A4 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin H2 (cytosol to extracellular)
2. (R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)

Catalysed by SLCO2A1, GLO1, GLOD4extracellular space, cytosolOne of 2 routes

1. transport of GSH and prostaglandin H2 (cytosol to extracellular)
2. alcohol dehydrogenase (formaldehyde)

Catalysed by SLCO2A1, ADH1C, ADH1A, ADH5 and 3 moreextracellular space, cytosol

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of dehydroepiandrosterone sulfate (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of leukotriene C4 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 6 routes

1. transport of GSH and prostaglandin H2 (cytosol to extracellular)
2. Glutathione: 5-HPETE oxidoreductase

Catalysed by SLCO2A1, GPX5, GPX1, GPX2 and 6 moreextracellular space, cytosolOne of 13 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of histamine (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin H2 (cytosol to extracellular)
2. Sulfide:glutathione,quinone oxidoreductase

Catalysed by SLCO2A1, SQORextracellular space, cytosol, mitochondrial matrix

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of dopamine (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. prostaglandin H2(out) + 2 (S)-lactate(in) = prostaglandin H2(in) + 2 (S)-lactate(out)
2. (2S)-2-phospholactate + H2O = (S)-lactate + phosphate

Catalysed by SLCO2A1, PGPinner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of estrone 3-sulfate (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. transport of GSH and prostaglandin H2 (cytosol to extracellular)
2. glutathione gamma-glutamylaminopeptidase

Catalysed by SLCO2A1, GGTLC3, GGT1, GGT5 and 3 moreextracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of noradrenaline (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of prostaglandin G2 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

1. prostaglandin-D synthase (prostaglandin H2)
2. prostaglandin D2 + NADPH + H(+) = 11beta-prostaglandin F2 + NADP(+)

Catalysed by HPGDS, PTGDS, AKR1C3, AKR1C2cytosol

1. thromboxane A synthase (prostaglandin H2)
2. thromboxane A2 hydrolysis

Catalysed by TBXAS1endoplasmic reticulumOne of 8 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. solute carrier organic anion transporter (S-glutathionyl-2-4-dinitrobenzene)

Catalysed by SLCO1B1, SLCO1A2, SLC7A9, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of arachidonate (cytosol to extracellular)
3. Utilized Transport

Catalysed by SLCO1B1extracellular space, cytosol, endoplasmic reticulumOne of 2 routes

1. transport of prostaglandin H2 (cytosol to extracellular)
2. transport of serotonin (cytosol to extracellular)
3. acetyl-CoA:aralkylamine N-acetyltransferase

Catalysed by SLCO1B1, SLCO1A2