a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine

Three steps

• (3S)-3-hydroxy-3-methylglutaryl-CoAReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and acetoacetate (cytosol to extracellular)
  3. (3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 8 morecytosol, extracellular space

• 2-iminopropanoateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. 2-iminopropanoate + H2O = pyruvate + NH4(+)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + phosphocholine + H(+)
  2. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
  3. 1-O-hexadecyl-2-acetyl-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)

  Catalysed by ENPP7, PCYT1A, PCYT1B, CEPT1

• phosphoenolpyruvic acidReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. pyruvate kinase (dTDP)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 8 morecytosol, extracellular space

• 13-cis-retinalReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and retinoate (cytosol to extracellular)
  3. retinal dehydrogenase (13-cis-retinal)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 6 morecytosol, extracellular space, endoplasmic reticulum

• N-acetyl-beta-neuraminic acidReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• L-ornithineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N2-Acetyl-L-ornithine amidohydrolase
  3. N2-Acetyl-L-ornithine amidohydrolase

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 2 morecytosol

• an N-acylsphing-4-enineReach from here →
  1. CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase
  2. ceramide cholinephosphotransferase (CDP-choline)
  3. ceramide cholinephosphotransferase (CDP-choline)

  Catalysed by CHPT1, CEPT1cytosol, endoplasmic reticulumOne of 9 routes

• 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + phosphocholine + H(+)
  2. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
  3. 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CMP + H(+)

  Catalysed by ENPP7, PCYT1A, PCYT1B, CEPT1

• a 3-acylpyruvateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• acetoacetyl-CoAReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and acetoacetate (cytosol to extracellular)
  3. acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular spaceOne of 2 routes

• butanoyl-CoAReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and butyrate (cytosol to extracellular)
  3. Butanoate:CoA ligase (AMP-forming)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 11 morecytosol, extracellular spaceOne of 2 routes

• 1-hexadecanoyl-sn-glycero-3-phosphateReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + choline + H(+)

  Catalysed by LCAT, PLA2G7, ENPP2, GDPD3 and 1 more

• a 1,2-diacyl-sn-glycero-3-phosphocholineReach from here →
  1. CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase
  2. ceramide cholinephosphotransferase (CDP-choline)
  3. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol

  Catalysed by CHPT1, CEPT1, SGMS1, SGMS2cytosol, endoplasmic reticulumOne of 2 routes

• 2-oxo-3-sulfanylpropanoateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• 2-methyl-3-oxopropanoateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• sphing-4-enineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 2 morecytosol

• N-acetyl-alpha-D-glucosamine 1-phosphateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
  3. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• spermidineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N(8)-acetylspermidine + H2O = spermidine + acetate
  3. N8-acetylspermidine to spermidine conversion

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 2 morecytosolOne of 2 routes

• L-methionineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 8 morecytosol, extracellular space

• a 2-acyl-sn-glycero-3-phosphocholineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphocholine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• L-alanineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space, mitochondrial matrixOne of 18 routes

• a 1-acyl-sn-glycero-3-phosphocholineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• cadaverineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-acetylcadaverine + H2O = cadaverine + acetate
  3. N-acetylcadaverine + H2O = cadaverine + acetate

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 2 morecytosol

• (3S)-citramalyl-CoAReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• an S-substituted L-cysteineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
  3. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 2 morecytosol

• D-glucosamine 6-phosphateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
  3. D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosolOne of 2 routes

• 5-amino-2-oxopentanoateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• (4R)-4-hydroxy-2-oxoglutarateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• an all-trans-retinyl esterReach from here →
  1. CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase
  2. diacylglycerol cholinephosphotransferase (1,2-diacylglycerol-LD-PC pool)
  3. Lecithin Retinol Acyltransferase

  Catalysed by CHPT1, CEPT1, LRATcytosolOne of 4 routes

• a 1-acyl-sn-glycero-3-phospho-L-serineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• a 1-acyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + 1-hexadecanoyl-sn-glycero-3-phosphocholine = a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine

  Catalysed by LCAT, PLA2G7, ASPG

• a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphoethanolamine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• a 2-acyl-sn-glycero-3-phospho-L-serineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• 2-acetamido-2-deoxy-D-glucopyranose 1-phosphateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
  3. phosphoglucomutase (N-acetylglucosamine-6-phosphate)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• (4S)-4-hydroxy-2-oxoglutarateReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. transport of acetate and pyruvate (cytosol to extracellular)
  3. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosol, extracellular space

• 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine

  Catalysed by LCAT, PLA2G7, PLA2G4C

• 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosol

• 1,2-dihexadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase
  2. ceramide cholinephosphotransferase (CDP-choline)
  3. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine = 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin

  Catalysed by CHPT1, CEPT1, SGMS2cytosol, endoplasmic reticulumOne of 5 routes

• 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. octadecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by LCAT, PLA2G7, LPCAT3

• 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. 1-hexadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

  Catalysed by LCAT, PLA2G7, LPCAT3, MBOAT1 and 3 moreOne of 3 routes

• 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA

  Catalysed by LCAT, PLA2G7, LPCAT3, MBOAT2 and 1 more

• 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA

  Catalysed by LCAT, PLA2G7, LPCAT3, MBOAT7One of 2 routes

• 1-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosolOne of 3 routes

• 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
  3. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine

  Catalysed by LCAT, PLA2G7, ASPG, PLA2G4C

• a 1-O-alkylglycerone 3-phosphateReach from here →
  1. a 1-organyl-2-lyso-sn-glycero-3-phospholipid + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine = a 1-organyl-2-acetyl-sn-glycero-3-phospholipid + a 1-O-alkyl-sn-glycero-3-phosphocholine
  2. a 1-O-alkyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphate + choline + H(+)
  3. a 1-O-alkylglycerone 3-phosphate + NADPH + H(+) = a 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)

  Catalysed by PAFAH2, ENPP2, GDPD1, DHRS7B

• 1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 3 morecytosolOne of 3 routes

• 4-acetamidobutanalReach from here →
  1. 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
  2. N-acetylputrescine + H2O = putrescine + acetate
  3. N-Acetylputrescine:oxygen oxidoreductase(deaminating)(flavin-containing)

  Catalysed by PAFAH1B1, PAFAH1B2, PAFAH1B3, ASPG and 7 morecytosolOne of 2 routes