Compound
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
An anionic phospholipid obtained by deprotonation of the phosphate OH group of any 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol); major species at pH 7.3.
Definition from ChEBI (CHEBI:64840), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C7H13O9PR
- Mass
- 272.147 g/mol
- Charge
- -1
- SMILES
- *C(=O)OC[C@@H](O)COP(=O)([O-])OC[C@@H](O)CO
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- GPAMProteinUNIPROT:Q9HCL2substrate ofInferred only32 paths32 endpoints
- LPCAT1ProteinUNIPROT:Q8NF37substrate ofInferred only24 paths12 endpoints
- SPNS1ProteinUNIPROT:Q9H2V7transported byInferred only20 paths20 endpoints
- LCLAT1ProteinUNIPROT:Q6UWP7substrate ofInferred only16 paths8 endpoints
- TAFAZZINProteinUNIPROT:Q16635substrate ofInferred only8 paths8 endpoints
- CLN5ProteinUNIPROT:O75503substrate ofInferred only1 path1 endpoint
What the reference databases state
Chemical structure
- 1-acyl-sn-glycero-3-phospho-(3'-acyl-sn-1'-glycerol) has the functional parent 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)CompoundChEBI CHEBI:232628Inferred only
Statements
8 statements
8 statements · 1 reference database · Subject: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) · Sources: Rhea
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of CLN5ProteinRhea RHEA:77619Inferred only
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of GPAMProteinRhea RHEA:33203Inferred only
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of LCLAT1ProteinRhea RHEA:37619Inferred only
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of LCLAT1ProteinRhea RHEA:33203Inferred only
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of LPCAT1ProteinRhea RHEA:37807Inferred only
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of LPCAT1ProteinRhea RHEA:33203Inferred only
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of TAFAZZINProteinRhea RHEA:67748Inferred only
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) is transported by SPNS1ProteinRhea RHEA:74443Inferred only
Reactions
9 reactions
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+coenzyme A(4-)
Catalysed by LCLAT1 or LPCAT1 or GPAM
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33203CC BY 4.0Reference data
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+(9Z)-octadecenoyl-CoA1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)+coenzyme A(4-)
Catalysed by LCLAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:37619CC BY 4.0Reference data
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+hexadecanoyl-CoA1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)+coenzyme A(4-)
Catalysed by LPCAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:37807CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+water1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+a fatty acid+hydron
Catalysed by PLA2G15
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:44416CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+a 1-acyl-sn-glycero-3-phosphocholine1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+a 1,2-diacyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:67676CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphate+a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+a 1,2-diacyl-sn-glycero-3-phosphate
Catalysed by TAFAZZIN
Reaction pageReversibleBalance undeterminable
Rhea RHEA:67748CC BY 4.0Reference data
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+hydron1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+hydron
Transported by SPNS1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:74443CC BY 4.0Reference data
21-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)1-acyl-sn-glycero-3-phospho-(3'-acyl-sn-1'-glycerol)+sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by CLN5
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:77619CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+N-(acetyl)-sphing-4-enine1-O-acyl-N-(acetyl)-sphing-4-enine+1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by PLA2G15
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:78363CC BY 4.0Reference data
Where it reaches
5 systems, 12 regions, 20 tissues, 20 transporter routes — routes, not measurements: transporters known to carry 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) are expressed there, and no source reports it arriving.
Loading the model…
Other names
3 names
Resolves to: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
- Also called
- 1-acyl-sn-glycero-3-phosphonato-(1'-sn-glycerol)LPG
- Systematic name
- (2S)-3-alkanoyloxy-2-hydroxypropyl (2R)-2,3-dihydroxypropyl phosphate