Compound

cadaverine

A foul-smelling diamine formed by bacterial decarboxylation of lysine. It is also an intermediate secondary metabolite in lysine-derived alkaloid biosynthetic pathways (e.g., quinolizidines and lycopodium).

Definition from MeSH (D002103), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:58384ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of cadaverine — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, cation
Formula: C5H16N2
Mass: 104.197 g/mol
Charge: +2
InChIKey: VHRGRCVQAFMJIZ-UHFFFAOYSA-P
SMILES: [NH3+]CCCCC[NH3+]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Chemical structure

N-acetylcadaverine has the functional parent cadaverineCompoundChEBI CHEBI:134408Inferred only

Statements

4 statements

4 statements · 1 reference database · Subject: cadaverine · Sources: Rhea

Order

cadaverine is converted to 5-aminopentanalCompoundRhea RHEA:69132Inferred only
5-aminopentanal is converted to cadaverineCompoundRhea RHEA:69132Inferred only
cadaverine is a substrate of AOC1ProteinRhea RHEA:69132Inferred only
cadaverine is a substrate of HDAC10ProteinRhea RHEA:51892Inferred only

Reactions

10 reactions

L-lysine+hydroncadaverine+carbon dioxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:22352CC BY 4.0Reference data
cadaverine+L-lysinecadaverine+L-lysine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:28895CC BY 4.0Reference data
cadaverine+hydroncadaverine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:29711CC BY 4.0Reference data
cadaverine+S-adenosyl 3-(methylsulfanyl)propylamineCHEBI:64858+S-methyl-5'-thioadenosine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:33387CC BY 4.0Reference data
N-acetylcadaverine+watercadaverine+acetate
Catalysed by HDAC10
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:51892CC BY 4.0Reference data
D-lysine+hydroncadaverine+carbon dioxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:59052CC BY 4.0Reference data
cadaverine+2-oxoglutarate(2-)5-aminopentanal+L-glutamate(1-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:61624CC BY 4.0Reference data
cadaverine+dioxygen+water5-aminopentanal+hydrogen peroxide+ammonium
Catalysed by AOC1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:69132CC BY 4.0Reference data
cadaverine+L-glutamate(1-)+ATP(4-)CHEBI:193053+ADP(3-)+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:73899CC BY 4.0Reference data
cadaverine+acetyl-CoAN-acetylcadaverine+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79547CC BY 4.0Reference data

Other names

2 names

Resolves to: cadaverine

Also called: pentane-1,5-diaminium
Systematic name: pentane-1,5-bis(aminium)