Compound
a 1-acyl-sn-glycero-3-phosphocholine
The ammonium betaine of a 1-O-acyl-sn-glycero-3-phosphocholine arising from deprotonation of the phosphate OH; major species at pH 7.3.
Definition from ChEBI (CHEBI:58168), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound
- Formula
- C9H19NO7PR
- Mass
- 284.224 g/mol
- Charge
- 0
- SMILES
- [1*]C(=O)OC[C@@H](O)COP(=O)([O-])OCC[N+](C)(C)C
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
24 entities
24 entities reached.
0 reported hops24 assembled from the scaffold
- PLA2G4AProteinUNIPROT:P47712substrate ofInferred only61 paths61 endpoints
- LPCAT4ProteinUNIPROT:Q643R3substrate ofInferred only27 paths9 endpoints
- LPCAT3ProteinUNIPROT:Q6P1A2substrate ofInferred only24 paths8 endpoints
- LPCAT1ProteinUNIPROT:Q8NF37substrate ofInferred only24 paths12 endpoints
- PLA2G6ProteinUNIPROT:O60733substrate ofInferred only23 paths23 endpoints
- SPNS1ProteinUNIPROT:Q9H2V7transported byInferred only20 paths20 endpoints
- PLA2G4BProteinUNIPROT:P0C869substrate ofInferred only20 paths20 endpoints
- LIPCProteinUNIPROT:P11150substrate ofInferred only18 paths18 endpoints
- PRDX6ProteinUNIPROT:P30041substrate ofInferred only15 paths15 endpoints
- LCATProteinUNIPROT:P04180substrate ofInferred only13 paths13 endpoints
- ASPGProteinUNIPROT:Q86U10substrate ofInferred only12 paths3 endpoints
- PLA2G4CProteinUNIPROT:Q9UP65substrate ofInferred only12 paths12 endpoints
Show the remaining 12
- PLB1ProteinUNIPROT:Q6P1J6substrate ofInferred only10 paths10 endpoints
- TAFAZZINProteinUNIPROT:Q16635substrate ofInferred only8 paths8 endpoints
- MBOAT1ProteinUNIPROT:Q6ZNC8substrate ofInferred only7 paths7 endpoints
- MBOAT2ProteinUNIPROT:Q6ZWT7substrate ofInferred only6 paths6 endpoints
- MFSD2AProteinUNIPROT:Q8NA29transported byInferred only6 paths6 endpoints
- PNPLA8ProteinUNIPROT:Q9NP80substrate ofInferred only6 paths6 endpoints
- ENPP2ProteinUNIPROT:Q13822substrate ofInferred only5 paths5 endpoints
- ENPP6ProteinUNIPROT:Q6UWR7substrate ofInferred only5 paths5 endpoints
- PNPLA7ProteinUNIPROT:Q6ZV29substrate ofInferred only5 paths5 endpoints
- LPCAT2ProteinUNIPROT:Q7L5N7substrate ofInferred only5 paths5 endpoints
- PNPLA6ProteinUNIPROT:Q8IY17substrate ofInferred only5 paths5 endpoints
- PLA2G15ProteinUNIPROT:Q8NCC3substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
34 statements
34 statements · 1 reference database · Subject: a 1-acyl-sn-glycero-3-phosphocholine · Sources: Rhea
- a 1-acyl-sn-glycero-3-phosphocholine is converted to a 2-acyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:24356Inferred only
- a 2-acyl-sn-glycero-3-phosphocholine is converted to a 1-acyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:24356Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:44708Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:32991Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:44652Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of ENPP2ProteinRhea RHEA:38995Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of ENPP6ProteinRhea RHEA:44720Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LCATProteinRhea RHEA:21204Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LIPCProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:12937Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37803Inferred only
Show the remaining 22
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT2ProteinRhea RHEA:12937Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:12937Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:37559Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:37563Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT4ProteinRhea RHEA:12937Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT4ProteinRhea RHEA:37803Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of LPCAT4ProteinRhea RHEA:33359Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of MBOAT1ProteinRhea RHEA:12937Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of MBOAT2ProteinRhea RHEA:12937Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4AProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4BProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G6ProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PLB1ProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PNPLA6ProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PNPLA7ProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PNPLA8ProteinRhea RHEA:15177Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of PRDX6ProteinRhea RHEA:12937Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is a substrate of TAFAZZINProteinRhea RHEA:33731Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is transported by MFSD2AProteinRhea RHEA:44376Inferred only
- a 1-acyl-sn-glycero-3-phosphocholine is transported by SPNS1ProteinRhea RHEA:74435Inferred only
Reactions
49 reactions
a 1-acyl-sn-glycero-3-phosphocholine+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by PRDX6 or LPCAT4 or LPCAT3 or MBOAT1 or MBOAT2 or LPCAT2 or LPCAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12937CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphocholine+watersn-glycerol 3-phosphocholine+a fatty acid+hydron
Catalysed by PLA2G6 or PLA2G4B or LIPC or PLA2G4A or PLB1 or PNPLA7 or ASPG or PNPLA6 or PLA2G15 or PNPLA8 or PLA2G4C
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:15177CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+watera 1-acyl-sn-glycero-3-phosphocholine+a fatty acid+hydron
Catalysed by PLA2G10 or PLA2G6 or PLA2G1B or PLA2G4B or PLA2G2A or PRDX6 or PLA2G5 or PNPLA4 or PLA2G4A or PLAAT3 or PLA2G4E or PLA2G4F and 18 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:15801CC BY 4.0Reference data
a di-trans,poly-cis-dolichol+a 1,2-diacyl-sn-glycero-3-phosphocholinean acyl-di-trans,poly-cis-dolichol+a 1-acyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:19285CC BY 4.0Reference data
a sterol+a 1,2-diacyl-sn-glycero-3-phosphocholinea sterol ester+a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by LCAT
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:21204CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphocholinea 2-acyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24356CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+a 1,2-diacyl-sn-glycero-3-phosphocholinea triacyl-sn-glycerol+a 1-acyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32843CC BY 4.0Reference data
a 2-acylglycerol+a 1,2-diacyl-sn-glycero-3-phosphocholinea 1-acyl-sn-glycero-3-phosphocholine+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32851CC BY 4.0Reference data
a 1-acyl-sn-glycerol+a 1,2-diacyl-sn-glycero-3-phosphocholinea 1-acyl-sn-glycero-3-phosphocholine+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32859CC BY 4.0Reference data
2a 1-acyl-sn-glycero-3-phosphocholinesn-glycerol 3-phosphocholine+a 1,2-diacyl-sn-glycero-3-phosphocholine
Catalysed by ASPG
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32991CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphocholine+(9Z)-octadecenoyl-CoAa 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33359CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+a 1,2-diacyl-sn-glycero-3-phosphocholinea cardiolipin+a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by TAFAZZIN
Reaction pageReversibleBalance undeterminable
Rhea RHEA:33731CC BY 4.0Reference data
Where it reaches
6 systems, 13 regions, 25 tissues, 26 transporter routes — routes, not measurements: transporters known to carry a 1-acyl-sn-glycero-3-phosphocholine are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: a 1-acyl-sn-glycero-3-phosphocholine
- Also called
- 1-acyl-sn-glycero-3-phosphocholineLPC