Compound
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine
A 2-acyl-1-alkyl-sn-glycero-3-phosphocholine where the 2-O-acyl group is specified as acetyl; a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
Definition from ChEBI (CHEBI:36707), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound
- Formula
- C10H21NO7PR
- Mass
- 298.25 g/mol
- Charge
- 0
- SMILES
- *OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(C)=O
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
17 entities
17 entities reached.
0 reported hops17 assembled from the scaffold
- PAFAH1B1ProteinUNIPROT:P43034substrate ofInferred only128 paths64 endpoints
- PAFAH1B3ProteinUNIPROT:Q15102substrate ofInferred only108 paths36 endpoints
- ATP8B1ProteinUNIPROT:O43520transported byInferred only81 paths79 endpoints
- PAFAH1B2ProteinUNIPROT:P68402substrate ofInferred only78 paths26 endpoints
- ABCA1ProteinUNIPROT:O95477transported byInferred only47 paths47 endpoints
- LCATProteinUNIPROT:P04180substrate ofInferred only26 paths13 endpoints
- PLA2G7ProteinUNIPROT:Q13093substrate ofInferred only15 paths5 endpoints
- LPCAT1ProteinUNIPROT:Q8NF37substrate ofInferred only12 paths12 endpoints
- CHPT1ProteinUNIPROT:Q8WUD6substrate ofInferred only10 paths10 endpoints
- CEPT1ProteinUNIPROT:Q9Y6K0substrate ofInferred only10 paths10 endpoints
- LPCAT4ProteinUNIPROT:Q643R3substrate ofInferred only9 paths9 endpoints
- ASPGProteinUNIPROT:Q86U10substrate ofInferred only9 paths3 endpoints
Show the remaining 5
- ABCB4ProteinUNIPROT:P21439transported byInferred only8 paths7 endpoints
- PAFAH2ProteinUNIPROT:Q99487substrate ofInferred only8 paths2 endpoints
- ENPP7ProteinUNIPROT:Q6UWV6substrate ofInferred only5 paths5 endpoints
- LPCAT2ProteinUNIPROT:Q7L5N7substrate ofInferred only5 paths5 endpoints
- ATP8B2ProteinUNIPROT:P98198transported byInferred only3 paths3 endpoints
What the reference databases state
Statements
33 statements
33 statements · 2 reference databases · Subject: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine · Sources: Human-GEM, Rhea
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is converted to a 1-O-alkyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:18461Inferred only
- a 1-O-alkyl-sn-glycero-3-phosphocholine is converted to a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:18461Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinHuman-GEM MAR07611Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:17777Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinHuman-GEM MAR08518Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of CEPT1ProteinHuman-GEM MAR07610Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of CHPT1ProteinHuman-GEM MAR07610Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of ENPP7ProteinRhea RHEA:63380Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of LCATProteinRhea RHEA:17777Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of LCATProteinRhea RHEA:53636Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:18461Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of LPCAT2ProteinRhea RHEA:18461Inferred only
Show the remaining 21
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of LPCAT4ProteinRhea RHEA:18461Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B1ProteinHuman-GEM MAR08518Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B1ProteinHuman-GEM MAR07611Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B2ProteinRhea RHEA:17777Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B2ProteinHuman-GEM MAR07611Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B2ProteinHuman-GEM MAR08518Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B3ProteinRhea RHEA:17777Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B3ProteinHuman-GEM MAR08518Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH1B3ProteinHuman-GEM MAR07611Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH2ProteinHuman-GEM MAR08518Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH2ProteinHuman-GEM MAR07611Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH2ProteinRhea RHEA:11048Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PAFAH2ProteinRhea RHEA:17777Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PLA2G7ProteinRhea RHEA:17777Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PLA2G7ProteinHuman-GEM MAR07612Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is a substrate of PLA2G7ProteinHuman-GEM MAR08519Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is transported by ABCA1ProteinHuman-GEM MAR11582Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is transported by ABCB4ProteinHuman-GEM MAR11582Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is transported by ATP10AProteinHuman-GEM MAR11582Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is transported by ATP8B1ProteinHuman-GEM MAR11582Inferred only
- a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is transported by ATP8B2ProteinHuman-GEM MAR11582Inferred only
Reactions
16 reactions
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholinea 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine
Reaction pageReversibleBalance undeterminablecytosol, extracellular space
Human-GEM MAR07608CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycerol+CHEBI:16436a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+cytidine 5'-monophosphate+proton
Reaction pageReversibleBalance undeterminableEC 2.7.8.2cytosol
Human-GEM MAR07610CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+waterMAM00549c+acetate+proton
Catalysed by PAFAH1B1 or PAFAH1B3 or PAFAH2 or ASPG or PAFAH1B2
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.47cytosol
Human-GEM MAR07611CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+waterMAM00549e+acetate+proton
Catalysed by PLA2G7
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.47extracellular space
Human-GEM MAR07612CC BY 4.0Reference data
MAM00549c+CHEBI:15351a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+CHEBI:1146900
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.67cytosol
Human-GEM MAR07613CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+waterMAM00516c+acetate+proton
Catalysed by PAFAH1B1 or PAFAH1B3 or PAFAH2 or ASPG or PAFAH1B2
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.47cytosol
Human-GEM MAR08518CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+waterMAM00516e+acetate+proton
Catalysed by PLA2G7
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.47extracellular space
Human-GEM MAR08519CC BY 4.0Reference data
MAM00516c+CHEBI:15351a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+CHEBI:1146900
Catalysed by LPCAT2 or LPCAT1 or LPCAT4
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.67cytosol
Human-GEM MAR08521CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09171CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+ATP+watera 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+ADP+proton+phosphate(3-)
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalance undeterminableEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11582CC BY 4.0Reference data
a 1-organyl-2-lyso-sn-glycero-3-phospholipid+a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholinea 1-organyl-2-acetyl-sn-glycero-3-phospholipid+a 1-O-alkyl-sn-glycero-3-phosphocholine
Catalysed by PAFAH2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11048CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycero-3-phosphocholine+acetate+hydron
Catalysed by LCAT or PAFAH1B2 or PLA2G7 or PAFAH1B3 or ASPG or PAFAH2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17777CC BY 4.0Reference data
Where it reaches
10 systems, 25 regions, 85 tissues, 86 transporter routes — routes, not measurements: transporters known to carry a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine are expressed there, and no source reports it arriving.
Loading the model…
Other names
5 names
Resolves to: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine
- Also called
- 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine1-alkyl-2-acetyl-sn-glycero-3-phosphocholines1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine2-acetyl-1-alkyl-sn-glycero-3-phosphocholine zwitterionplatelet-activating factor