N-octanoylglycine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

461 compounds within 3 steps: 4 in 1, 92 in 2, 365 in 3

Two steps

CHEBI:240943Reach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. glycine N-acyltransferase (2-methylbutyryl-CoA)
Catalysed by GLYATL2, GLYAT, GLYATL1mitochondrial matrix
octanoateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. Octanoyl-CoA hydrolase
Catalysed by GLYATL2, ACOT7cytosolOne of 2 routes
phenylacetylglycineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. phenylacetyl-CoA:glycine N-phenylacetyltransferase
Catalysed by GLYATL2, GLYATcytosolOne of 3 routes
CHEBI:27540Reach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. Fatty Acid Beta Oxidation (C8->C6), Peroxisomal
Catalysed by GLYATL2, ACAA1, HSD17B4, EHHADH and 1 moreperoxisome
CHEBI:28666Reach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. LTD4 hydrolysis
Catalysed by GLYATL2cytosol
Cu(2+)Reach from here →
1. N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. Cu(2+)(out) + L-ascorbate(in) = Cu(+)(out) + monodehydro-L-ascorbate radical(in) + H(+)
Catalysed by PAM, CYBRD1inner side of the membrane, outer side of the membrane
L-ascorbic acidReach from here →
1. N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
Catalysed by PAMOne of 10 routes
Gly-tRNA(Gly)Reach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. glycine:tRNA(Gly) ligase (AMP-forming)
Catalysed by GLYATL2, GARS1cytosol
chlorine(.)Reach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. transport of chloride and glycine (cytosol to extracellular)
Catalysed by GLYATL2, SLC6A9, SLC6A14extracellular space, cytosolOne of 3 routes
glycocholateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by GLYATL2, BAATperoxisomeOne of 3 routes
5-aminolevulinateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA
Catalysed by GLYATL2, ALAS1, ALAS2
glycochenodeoxycholateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)
Catalysed by GLYATL2, BAAT
glycochenodeoxycholic acidReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by GLYATL2, BAATperoxisomeOne of 3 routes
glyoxylateReach from here →
1. N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. N-octanoyl-(2S)-hydroxyglycine = octanamide + glyoxylate
Catalysed by PAMOne of 12 routes
glycolithocholic acidReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. bile acid-CoA:amino acid N-acyltransferase (glycine)
Catalysed by GLYATL2, BAATcytosolOne of 2 routes
L-2-amino-3-oxobutanoic acidReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. Acetyl-CoA:glycine C-acetyltransferase
Catalysed by GLYATL2, GCATmitochondrial matrix
L-ornithineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. L-Arginine:glycine amidinotransferase
Catalysed by GLYATL2, GATMcytosolOne of 5 routes
S(8)-aminomethyldihydrolipoamideReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. dihydrolipoyl dehydrogenase ([protein]-N6-(lipoyl)lysine)
Catalysed by GLYATL2, GLDC, GCSHmitochondrial matrix
sarcosineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. sarcosine + O2 + H2O = formaldehyde + glycine + H2O2
Catalysed by GLYATL2, PIPOXOne of 2 routes
(6S)-5,6,7,8-tetrahydrofolateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
Catalysed by GLYATL2, SHMT1, SHMT2
an N-acylglycineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. an acyl-CoA + glycine = an N-acylglycine + CoA + H(+)
Catalysed by GLYATL2, GLYATL3, GLYAT
guanidinoacetateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. L-Arginine:glycine amidinotransferase
Catalysed by GLYATL2, GATMcytosolOne of 2 routes
L-methionineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. transport of glycine and methionine (cytosol to extracellular)
Catalysed by GLYATL2, SLC7A5extracellular space, cytosolOne of 5 routes
L-tryptophanReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. transport of glycine and tryptophan (cytosol to extracellular)
Catalysed by GLYATL2, SLC7A5extracellular space, cytosolOne of 5 routes
glutathioneReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
Catalysed by GLYATL2, GSS
L-alanineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. transport of alanine and glycine (cytosol to extracellular)
Catalysed by GLYATL2, SLC3A2, SLC7A5, SLC7A10extracellular space, cytosolOne of 6 routes
leukotriene C4Reach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. leukotriene C4 hydrolysis
Catalysed by GLYATL2cytosol
L-asparagineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. transport of asparagine and glycine (cytosol to extracellular)
Catalysed by GLYATL2extracellular space, cytosolOne of 4 routes
L-phenylalanineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. transport of glycine and phenylalanine (cytosol to extracellular)
Catalysed by GLYATL2, SLC7A5extracellular space, cytosolOne of 7 routes
L-tyrosineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
Catalysed by GLYATL2, AADAT
N(omega),N(omega)-dimethyl-L-arginineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. N(omega),N(omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine
Catalysed by GLYATL2, AGXT2
N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)
Catalysed by GLYATL2One of 2 routes
N-benzoylglycineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. Hippurate (Benzoylglycinate) Formation
Catalysed by GLYATL2mitochondrial matrixOne of 2 routes
decanoyl-CoAReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. fatty acyl-CoA synthase (N-C10:0CoA)
Catalysed by GLYATL2cytosol
(2E)-octenoyl-CoAReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. trans-oct-2-enoyl-CoA reductase
Catalysed by GLYATL2, MECRmitochondrial matrixOne of 5 routes
(2S)-2-aminobutanoateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
Catalysed by GLYATL2, AGXT2
1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. octanoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GLYATL2, LPCAT4
1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. octanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL2, LPCAT1
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GLYATL2, LCLAT1
1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GLYATL2, LCLAT1
1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GLYATL2, LPCAT4
glycodeoxycholateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. Glycodeoxycholate amidohydrolase
Catalysed by GLYATL2cytosolOne of 2 routes
N-tetradecanoylglycineReach from here →
1. N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
Catalysed by PAMOne of 2 routes
N-eicosanoylglycinateReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by GLYATL2, BAAT
N-docosanoylglycineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by GLYATL2, BAAT
N-hexacosanoylglycineReach from here →
1. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
2. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by GLYATL2, BAAT

Three steps

beta-carbolineReach from here →
Catalysed by GLYATL2, SLC7A5extracellular space, cytosol
(S)-carnitineReach from here →
Catalysed by GLYATL2, BAAT and 1 more