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Proteins/UNIPROT:P98198
Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane. May contribute to the maintenance of membrane lipid asymmetry..
Function from UniProtKB (P98198), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
20 statements
20 statements · 7 reference databases · Subject: ATP8B2 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
30 reactions
MAM00516c+ATP+waterMAM00516e+ADP+proton+phosphate(3-)
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalance undeterminableEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11572CC BY 4.0Reference data
4 names
Resolves to: ATP8B2
Reaction pageLeft to rightBalance undeterminableEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11582CC BY 4.0Reference data
ATP+water+MAM03827cADP+proton+phosphate(3-)+MAM03827e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11587CC BY 4.0Reference data
ATP+water+MAM03805cADP+proton+phosphate(3-)+MAM03805e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11588CC BY 4.0Reference data
ATP+water+MAM03806cADP+proton+phosphate(3-)+MAM03806e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11589CC BY 4.0Reference data
ATP+water+MAM03808cADP+proton+phosphate(3-)+MAM03808e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11590CC BY 4.0Reference data
ATP+water+1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineADP+proton+phosphate(3-)+1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11591CC BY 4.0Reference data
ATP+water+MAM03810cADP+proton+phosphate(3-)+MAM03810e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11592CC BY 4.0Reference data
ATP+water+MAM03811cADP+proton+phosphate(3-)+MAM03811e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11593CC BY 4.0Reference data
ATP+water+MAM03812cADP+proton+phosphate(3-)+MAM03812e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11594CC BY 4.0Reference data
ATP+water+MAM03813cADP+proton+phosphate(3-)+MAM03813e
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11595CC BY 4.0Reference data
ATP+water+1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineADP+proton+phosphate(3-)+1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11596CC BY 4.0Reference data