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Proteins/UNIPROT:Q13393
Function as phospholipase selective for phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity)..
Function from UniProtKB (Q13393), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
2 rows
178 statements
178 statements · 8 reference databases · Subject: PLD1 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
14 reactions
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Catalysed by PLD1 or PLD2 or PLD6
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00629CC BY 4.0Reference data
4 names
Resolves to: PLD1
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00642CC BY 4.0Reference data
water+phosphatidyl-L-serineproton+phosphatidic acid+L-seryl residue
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00660CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Catalysed by PLD1
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4mitochondrial matrix
Human-GEM MAR01586CC BY 4.0Reference data
water+1-phosphatidyl-1D-myo-inositolproton+myo-inositol+phosphatidic acid
Catalysed by PLD1
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4Golgi apparatus
Human-GEM MAR03781CC BY 4.0Reference data
water+1-phosphatidyl-1D-myo-inositolproton+myo-inositol+phosphatidic acid
Catalysed by PLD1
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4endoplasmic reticulum
Human-GEM MAR03786CC BY 4.0Reference data
water+phosphatidyl-L-serineproton+phosphatidic acid+L-seryl residue
Catalysed by PLD1
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4Golgi apparatus
Human-GEM MAR03791CC BY 4.0Reference data
water+phosphatidyl-L-serineproton+phosphatidic acid+L-seryl residue
Catalysed by PLD1
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4endoplasmic reticulum
Human-GEM MAR03798CC BY 4.0Reference data
water+1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineMAM00627c+ethanolamine+proton
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR07605CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4Golgi apparatus
Human-GEM MAR08523CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4endoplasmic reticulum
Human-GEM MAR08525CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+watera 1,2-diacyl-sn-glycero-3-phosphate+choline+hydron
Catalysed by PLD2 or PLD1 or ENPP2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14445CC BY 4.0Reference data