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Proteins/UNIPROT:O15085
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth..
Function from UniProtKB (O15085), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
80 statements
80 statements · 4 reference databases · Subject: ARHGEF11 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: ARHGEF11