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Proteins/UNIPROT:O00764
Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions..
Function from UniProtKB (O00764), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
1 row
41 statements
41 statements · 6 reference databases · Subject: PDXK · Sources: Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
6 reactions
ATP+pyridoxalADP+proton+CHEBI:18405
Catalysed by PDXK
Reaction pageLeft to rightBalancedEC 2.7.1.35cytosol
Human-GEM MAR04065CC BY 4.0Reference data
ATP+pyridoxineADP+proton+pyridoxine 5'-phosphate
Catalysed by PDXK
5 names
Resolves to: PDXK
Human-GEM MAR04066CC BY 4.0Reference data
ATP+MAM02815cADP+proton+MAM02816c
Catalysed by PDXK
Reaction pageLeft to rightBalancedEC 2.7.1.35cytosol
Human-GEM MAR04068CC BY 4.0Reference data
pyridoxal+ATP(4-)pyridoxal 5'-phosphate+ADP(3-)+hydron
Catalysed by PDXK
Reaction pageLeft to rightBalanced
Rhea RHEA:10224CC BY 4.0Reference data
CHEBI:57761+ATP(4-)CHEBI:58451+ADP(3-)+hydron
Catalysed by PDXK
Reaction pageLeft to rightBalanced
Rhea RHEA:25104CC BY 4.0Reference data
pyridoxine+ATP(4-)pyridoxine 5'-phosphate+ADP(3-)+hydron
Catalysed by PDXK
Reaction pageLeft to rightBalanced
Rhea RHEA:25108CC BY 4.0Reference data