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Proteins/UNIPROT:Q92540
Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation..
Function from UniProtKB (Q92540), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
69 statements
69 statements · 3 reference databases · Subject: SMG7 · Sources: gene ontology, Hetionet, Reactome
5 names
Resolves to: SMG7