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Proteins/UNIPROT:Q9BPX1
Catalyzes the NAD(+)-dependent oxidation of L-fucose, yielding L-fucono-1,5-lactone, which rapidly converts spontaneously to L-fucone-1,4-lactone. Can also act on D-arabinose and L-galactose, with lower catalytic efficiency. Does not use NADPH. May be the initial enzyme of the L-fucose degradation pathway in mammals..
Function from UniProtKB (Q9BPX1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
37 statements
37 statements · 4 reference databases · Subject: HSD17B14 · Sources: Hetionet, Reactome, Rhea, WikiPathways
4 reactions
7 names
Resolves to: HSD17B14
Human-GEM MAR01813CC BY 4.0Reference data
L-fucose+NAD(1-)CHEBI:81457+NADH(2-)+hydron
Catalysed by HSD17B14
Reaction pageLeft to rightBalanced
Rhea RHEA:81515CC BY 4.0Reference data
CHEBI:46994+NAD(1-)CHEBI:194242+NADH(2-)+hydron
Catalysed by HSD17B14
Reaction pageLeft to rightBalanced
Rhea RHEA:81519CC BY 4.0Reference data
CHEBI:37619+NAD(1-)CHEBI:182410+NADH(2-)+hydron
Catalysed by HSD17B14
Reaction pageLeft to rightBalanced
Rhea RHEA:81523CC BY 4.0Reference data