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Proteins/UNIPROT:P49759
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells..
Function from UniProtKB (P49759), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
59 statements
59 statements · 3 reference databases · Subject: CLK1 · Sources: gene ontology, Hetionet, WikiPathways
3 reactions
2 names
Resolves to: CLK1
Rhea RHEA:10596CC BY 4.0Reference data