a dicarboxylate
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
307 compounds within 3 steps: 14 in 1, 55 in 2, 238 in 3
Two steps
- a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
- thiosulfate(in) + sulfate(out) = thiosulfate(out) + sulfate(in)
Catalysed by SLC25A35, SLC25A34, SLC25A14, SLC25A30 and 2 moreinner side of the membrane, outer side of the membraneOne of 2 routes
- urate(out) + a dicarboxylate(in) = urate(in) + a dicarboxylate(out)
- transport of L-lactate and urate (cytosol to extracellular)
Catalysed by SLC22A6, SLC22A12inner side of the membrane, outer side of the membrane, extracellular space, cytosol
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)
- 1-O-(1,2-saturated-alkyl)-sn-glycerol + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + O2 = a 1-(1-hydroxyalkyl)-sn-glycerol + (6R)-L-erythro-6,7-dihydrobiopterin + H2O
Catalysed by SLC22A6, SLC22A8, AGMOinner side of the membrane, outer side of the membrane
- N-benzoylglycine(out) + a dicarboxylate(in) = N-benzoylglycine(in) + a dicarboxylate(out)
- benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+)
Catalysed by SLC22A6, SLC22A8, GLYATinner side of the membrane, outer side of the membrane
- N-benzoylglycine(out) + a dicarboxylate(in) = N-benzoylglycine(in) + a dicarboxylate(out)
- benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+)
Catalysed by SLC22A6, SLC22A8, GLYATinner side of the membrane, outer side of the membrane
- prostaglandin E2(out) + a dicarboxylate(in) = prostaglandin E2(in) + a dicarboxylate(out)
- prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+)
Catalysed by SLC22A6, HPGDinner side of the membrane, outer side of the membraneOne of 2 routes
- prostaglandin F2alpha(out) + a dicarboxylate(in) = prostaglandin F2alpha(in) + a dicarboxylate(out)
- prostaglandin-F synthase (prostaglandin F2alpha)
Catalysed by SLC22A6inner side of the membrane, outer side of the membrane, cytosolOne of 4 routes
- prostaglandin F2alpha(out) + a dicarboxylate(in) = prostaglandin F2alpha(in) + a dicarboxylate(out)
- aldo-keto reductase (prostaglandin D2)
Catalysed by SLC22A6, AKR1C3inner side of the membrane, outer side of the membrane, cytosol
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa
Catalysed by SLC22A6, SLC22A8, THinner side of the membrane, outer side of the membrane
- a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
- N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate
Catalysed by SLC25A35, SLC25A34, SGSHinner side of the membrane, outer side of the membrane
- a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
- dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
Catalysed by SLC25A35, SLC25A34, STSinner side of the membrane, outer side of the membrane
- urate(out) + a dicarboxylate(in) = urate(in) + a dicarboxylate(out)
- urate(out) + glutathione(in) = urate(in) + glutathione(out)
Catalysed by SLC22A6, SLC22A13inner side of the membrane, outer side of the membrane
- a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
- ATP:sulfate adenylyltransferase
Catalysed by SLC25A35, SLC25A34, PAPSS1, PAPSS2inner side of the membrane, outer side of the membrane, cytosolOne of 4 routes
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine
Catalysed by SLC22A6, SLC22A8, PAHinner side of the membrane, outer side of the membrane
- a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
- estrone 3-sulfate + H2O = estrone + sulfate + H(+)
Catalysed by SLC25A35, SLC25A34, STSinner side of the membrane, outer side of the membrane
- a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
- Transport of 5-Hydroxyindoleacetate
Catalysed by SLC25A35, SLC25A34, SLC4A1inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes
- (indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
- S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase
Catalysed by SLC22A6, SLC22A8, COMT, LRTOMTinner side of the membrane, outer side of the membrane, cytosol
Catalysed by SLC22A6, MPOinner side of the membrane, outer side of the membrane, nucleusOne of 3 routes
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)
- 1-O-(1,2-saturated-alkyl)-sn-glycerol + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + O2 = a 1-(1-hydroxyalkyl)-sn-glycerol + (6R)-L-erythro-6,7-dihydrobiopterin + H2O
Catalysed by SLC22A6, SLC22A8, AGMOinner side of the membrane, outer side of the membrane
Three steps
- a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
- transport of chloride and sulfate (cytosol to extracellular)
- Carnitine Transport by Atb0
Catalysed by SLC25A35, SLC25A34, SLC26A6, SLC6A14inner side of the membrane, outer side of the membrane, extracellular space, cytosol