a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))

1. UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase (LacCer pool)

Catalysed by B3GNT5cytosolOne of 3 routes

1. alpha 1,4-galactosyltransferase (P blood group) (LacCer pool)

Catalysed by A4GALTcytosolOne of 3 routes

1. beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase

Catalysed by LCT, GLB1, GLB1L, TMPPElysosome

1. beta-1,4-N-acetyl-galactosaminyltransferase (LacCer pool)

Catalysed by B4GALNT1cytosolOne of 3 routes

1. beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase

Catalysed by LCT, GLB1, GLB1L, TMPPElysosome

1. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = an isogloboside iGb3Cer (d18:1(4E)) + UDP + H(+)

Catalysed by A3GALT2

1. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)

Catalysed by ST3GAL5cytosolOne of 3 routes

1. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + 3'-phosphoadenylyl sulfate = beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + adenosine 3',5'-bisphosphate + H(+)

Catalysed by GAL3ST1

1. beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase
2. galactitol:NADP+ 1-oxidoreductase

Catalysed by LCT, GLB1, GLB1L, TMPPE and 1 morelysosome, cytosol

1. UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase (LacCer pool)
2. beta-1,4-galactosyltransferase (lc3Cer)

Catalysed by B3GNT5, B4GALT3, B4GALT4, B4GALT2 and 1 more

1. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
2. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
3. solute carrier (acetyl-CoA)

Catalysed by ST3GAL5, ST8SIA1, SLC33A1cytosolOne of 2 routes

1. beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase
2. D-Glucosyl-N-acylsphingosine glucohydrolase
3. UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase

Catalysed by and 4 more