a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-galactoside + an N-acylsphing-4-enine

Catalysed by GBA1, GBA2

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine

Catalysed by GBA1, GALC, GBA3, GBA2

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine

Catalysed by GBA1, GALC, GBA3, GBA2One of 2 routes

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)

Catalysed by GAL3ST1

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)

Catalysed by ST3GAL5

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
2. UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase

Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morecytosolOne of 7 routes

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
2. an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acyl-sphinga-4E,14Z-dienine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Catalysed by GBA1, GALC, and 1 more

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
2. acyl-CoA:sphingosine N-acyltransferase
3. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase

Catalysed by GBA1, GALC, GBA3, GBA2 and 8 moreGolgi apparatus, mitochondrial matrixOne of 17 routes

1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
3. cholesterol + AH2 + O2 = 25-hydroxycholesterol + A + H2O