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Reach

a 2-acylglycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

300 compounds within 3 steps: 9 in 1, 44 in 2, 247 in 3

Does it reach a compound?

Two steps

a 1,3-diacyl-sn-glycerolReach from here →
1. a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)
2. a 1,3-diacyl-sn-glycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)
Catalysed by MGLL, ABHD6, ABHD11
a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,2-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine
2. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine = a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by PLA2G15, PLAAT1
a fatty acyl-CoAReach from here →
1. a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
Catalysed by MGLL, ABHD6, ACSL3

Three steps

(S)-carnitineReach from here →
Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosolOne of 244 routes
CHEBI:12947Reach from here →

Page 2 of 6

Catalysed by MOGAT2, AWAT2, MOGAT1, SGMS1 and 2 more

cytosol

One of 5 routes

beta-D-fructose 1-phosphateReach from here →

a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)
glycerol + NADP(+) = D-glyceraldehyde + NADPH + H(+)
beta-D-fructose 1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate

Catalysed by MGLL, ABHD6, AKR1A1, AKR1B1 and 1 more

an N-acyl-sphinga-4E,14Z-dienineReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acyl-sphinga-4E,14Z-dienine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Catalysed by MOGAT2, AWAT2, MOGAT1, SGMS1 and 2 more

a 3-hydroxyacyl derivative of bacterial toxinReach from here →

a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)
a 3-(acyloxy)acyl derivative of bacterial toxin + H2O = a 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)
a 3-(acyloxy)acyl derivative of bacterial toxin + H2O = a 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)

Catalysed by MGLL, ABHD6, AOAH

a 2-acyl-6-alpha-D-glucosaminyl-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)
a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + a fatty acyl-CoA = a 2-acyl-6-alpha-D-glucosaminyl-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + CoA

Catalysed by MGLL, ABHD6, ACSL3, PIGW

a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by MOGAT2, AWAT2, MOGAT1, SELENOI and 2 more

a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by MOGAT2, AWAT2, MOGAT1, SELENOI and 2 more

a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by MOGAT2, AWAT2, MOGAT1, SELENOI and 2 more

a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by MOGAT2, AWAT2, MOGAT1, SELENOI and 2 more

an N-(fatty acyl)-glycineReach from here →

a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)
a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)

Catalysed by MGLL, ABHD6, ACSL3, GLYATL2

(7Z)-octadecenoyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosolOne of 3 routes

CHEBI:15345Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Acetoacetate:CoA ligase (AMP-forming)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 3 morecytosolOne of 2 routes

acetylcholineReach from here →

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)
Acetyl-CoA:choline O-acetyltransferase

Catalysed by PLA2G15, ENPP2, CHATcytosolOne of 3 routes

CHEBI:15380Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
5-aminolevulinate synthase (2-amino-3-oxoadipate)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 4 morecytosol, mitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
glycine N-acyltransferase (2-methylbutyryl-CoA)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosol, mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Production of Tiglylcarnitine

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 4 morecytosolOne of 2 routes

isobutyryl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
acetyl-CoA C-acyltransferase (3-oxo-4-methyl-pentanoyl-CoA)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosol, mitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
glycine-N-acyltransferase (3-methylcrotonoylglycine)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 3 morecytosol, mitochondrial matrix

isovaleryl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
glycine N-acyltransferase (isovalerylglycine)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosol, mitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Arachidonate:CoA ligase (AMP-forming)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 10 morecytosolOne of 11 routes

CHEBI:15519Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
propanoyl-CoA C-acyltransferase

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosol, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Palmitate:CoA ligase (AMP-forming)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 10 morecytosolOne of 11 routes

oleoyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Transport of octadecenoyl-CoA into Mitochondrial Matrix

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosolOne of 11 routes

phenylacetyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Phenylacetate:CoA ligase

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 2 morecytosolOne of 3 routes

propionyl-CoAReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Propanoate:CoA ligase (AMP-forming)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 5 morecytosolOne of 43 routes

an hexadecanoyl-acylglycerolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacylglycerol + CoA
a 1,2-diacylglycerol + H2O = a 1-acylglycerol + a fatty acid + H(+)
a 1-acylglycerol + hexadecanoyl-CoA = an hexadecanoyl-acylglycerol + CoA

Catalysed by MOGAT2, MOGAT3, LPGAT1, TMEM68 and 2 more

CHEBI:15650Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
N-acetyl-LTE4 to leukotriene E4 conversion

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 34 morecytosolOne of 2 routes

betaine aldehydeReach from here →

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)
choline dehydrogenase (choline)

Catalysed by PLA2G15, ENPP2, CHDHcytosolOne of 3 routes

CHEBI:15727Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 3 morecytosol

CHEBI:15746Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
diamine N-acetyltransferase (N1-acetylspermine)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 4 morecytosolOne of 2 routes

hexadecanoic acidReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
1,2-diacyl-sn-glycerol acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by MOGAT2, AWAT2, MOGAT1, LPLextracellular spaceOne of 12 routes

a 1-O-alkyl-sn-glycerolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacylglycerol + CoA
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacylglycerol = a 1-O-alkyl-sn-glycero-3-phosphocholine + a triacylglycerol
a 1-O-alkyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycerol + phosphocholine + H(+)

Catalysed by MOGAT2, MOGAT3, LPGAT1, TMEM68 and 2 more

CHEBI:15978Reach from here →

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)
sn-Glycero-3-phosphocholine glycerophosphohydrolase

Catalysed by PLA2G15, PLA2G6, PLA2G4B, LIPC and 8 morecytosol

cholesterolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine

Catalysed by MOGAT2, AWAT2, MOGAT1, SGMS1 and 3 moreOne of 3 routes

11-cis-retinolReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Palmitoyl-CoA:retinol O-acyltransferase

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 4 morecytosolOne of 3 routes

oxaloacetateReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
ATP citrate lyase (citrate)

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 3 morecytosol

CHEBI:16566Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acylsphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
N-acylsphingosine amidohydrolase

Catalysed by MOGAT2, AWAT2, MOGAT1, SGMS1 and 6 morecytosol

1-acyl-sn-glycerol 3-phosphateReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
1,2-diacyl-sn-glycerol acylhydrolase
ATP:acylglycerol 3-phosphotransferase

Catalysed by MOGAT2, AWAT2, MOGAT1, LIPF and 15 moreextracellular space, cytosolOne of 6 routes

a cholesterol esterReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
diacylglycerol cholinephosphotransferase (1,2-diacylglycerol-LD-PC pool)
Phosphatidylcholine:sterol O-acyltransferase

Catalysed by MOGAT2, AWAT2, MOGAT1, CHPT1 and 2 morecytosolOne of 2 routes

myo-inositolReach from here →

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine
a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)

Catalysed by PLA2G15, ASPG, CDIPT

anilineReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Acetyl-CoA:arylamine N-acetyltransferase

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 4 morecytosol

CHEBI:17312Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
N1,N12-diacetylspermine to N1-acetylspermine conversion

Catalysed by MOGAT2, AWAT2, MOGAT1, DGAT1 and 2 morecytosolOne of 2 routes

all-trans-retinolReach from here →

a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)
an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H(+)
carboxylesterase (retinyl-ester)

Catalysed by MGLL, ABHD6, RPE65, CES2 and 19 morecytosolOne of 2 routes

linoleic acidReach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
1,2-diacyl-sn-glycerol acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by MOGAT2, AWAT2, MOGAT1, LPLextracellular spaceOne of 12 routes

AH2Reach from here →

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)
choline + A = betaine aldehyde + AH2

Catalysed by PLA2G15, ENPP2, CHDH

1-O-acyl-sn-glycero-3-phosphocholine(1+)Reach from here →

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
diacylglycerol cholinephosphotransferase (1,2-diacylglycerol-LD-PC pool)
phosphatidylcholine 2-acylhydrolase

Catalysed by MOGAT2, AWAT2, MOGAT1, CHPT1 and 19 morecytosol, endoplasmic reticulumOne of 8 routes