What it touches on the way
Mechanistic reach
40 entities
40 entities reached.
0 reported hops40 assembled from the scaffold
- CYP3A4ProteinUNIPROT:P08684metabolized byInferred only169 paths43 endpoints
- CYP2E1ProteinUNIPROT:P05181metabolized byInferred only140 paths35 endpoints
- CYP2C9ProteinUNIPROT:P11712metabolized byInferred only125 paths32 endpoints
- ACSL1ProteinUNIPROT:P33121substrate ofInferred only118 paths30 endpoints
- ACSL3ProteinUNIPROT:O95573substrate ofInferred only116 paths29 endpoints
- CYP1A2ProteinUNIPROT:P05177metabolized byInferred only116 paths29 endpoints
- CYP2C8ProteinUNIPROT:P10632metabolized byInferred only106 paths28 endpoints
- FABP5ProteinUNIPROT:Q01469transported byInferred only101 paths93 endpoints
- ACSL4ProteinUNIPROT:O60488substrate ofInferred only92 paths23 endpoints
- CD36ProteinUNIPROT:P16671transported byInferred only82 paths77 endpoints
- CYP2B6ProteinUNIPROT:P20813metabolized byInferred only78 paths21 endpoints
- CYP1B1ProteinUNIPROT:Q16678metabolized byInferred only77 paths20 endpoints
Show the remaining 28
- CYP2C19ProteinUNIPROT:P33261metabolized byInferred only76 paths19 endpoints
- SLC27A2ProteinUNIPROT:O14975substrate ofInferred only66 paths22 endpoints
- CYP1A1ProteinUNIPROT:P04798metabolized byInferred only65 paths20 endpoints
- CYP2U1ProteinUNIPROT:Q7Z449metabolized byInferred only60 paths15 endpoints
- CYP2D6ProteinUNIPROT:P10635metabolized byInferred only58 paths16 endpoints
- CYP3A5ProteinUNIPROT:P20815metabolized byInferred only44 paths11 endpoints
- CYP2A13ProteinUNIPROT:Q16696metabolized byInferred only44 paths11 endpoints
- ACSL6ProteinUNIPROT:Q9UKU0substrate ofInferred only44 paths11 endpoints
- ACSL5ProteinUNIPROT:Q9ULC5substrate ofInferred only44 paths11 endpoints
- CYP4B1ProteinUNIPROT:P13584metabolized byInferred only36 paths12 endpoints
- CYP2A7ProteinUNIPROT:P20853metabolized byInferred only36 paths9 endpoints
- CYP2F1ProteinUNIPROT:P24903metabolized byInferred only36 paths9 endpoints
- CYP3A43ProteinUNIPROT:Q9HB55metabolized byInferred only36 paths9 endpoints
- ALOX15ProteinUNIPROT:P16050substrate ofInferred only32 paths32 endpoints
- CYP2J2ProteinUNIPROT:P51589metabolized byInferred only32 paths8 endpoints
- CYP4F11ProteinUNIPROT:Q9HBI6metabolized byInferred only27 paths7 endpoints
- CYP4F12ProteinUNIPROT:Q9HCS2metabolized byInferred only26 paths7 endpoints
- CYP4F8ProteinUNIPROT:P98187metabolized byInferred only24 paths6 endpoints
- SLC27A3ProteinUNIPROT:Q5K4L6transported byInferred only24 paths24 endpoints
- CYP2S1ProteinUNIPROT:Q96SQ9metabolized byInferred only17 paths5 endpoints
- SLC27A4ProteinUNIPROT:Q6P1M0substrate of, transported byInferred only15 paths15 endpoints
- ACSBG1ProteinUNIPROT:Q96GR2substrate ofInferred only14 paths7 endpoints
- ACSBG2ProteinUNIPROT:Q5FVE4substrate ofInferred only12 paths6 endpoints
- ALOX15BProteinUNIPROT:O15296substrate ofInferred only11 paths11 endpoints
- FABP3ProteinUNIPROT:P05413transported byInferred only9 paths9 endpoints
- CYP4Z1ProteinUNIPROT:Q86W10metabolized byInferred only8 paths2 endpoints
- FABP4ProteinUNIPROT:P15090transported byInferred only6 paths6 endpoints
- CYP2A6ProteinUNIPROT:P11509metabolized byInferred only4 paths1 endpoint
What the reference databases state
Chemical structure
- (24S)-hydroxycholesterol 3-linoleoate has the functional parent linoleic acidCompoundChEBI CHEBI:82875Inferred only
- (9Z,12Z)-octadecadienamide has the functional parent linoleic acidCompoundChEBI CHEBI:82984Inferred only
- 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycerol has the functional parent linoleic acidCompoundChEBI CHEBI:75450Inferred only
- 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol has the functional parent linoleic acidCompoundChEBI CHEBI:133484Inferred only
- 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol has the functional parent linoleic acidCompoundChEBI CHEBI:75614Inferred only
- 1-(9Z,12Z-octadecadienoyl)-glycerol has the functional parent linoleic acidCompoundChEBI CHEBI:75568Inferred only
- 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine has the functional parent linoleic acidCompoundChEBI CHEBI:76086Inferred only
- 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:28733Inferred only
- 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:60000Inferred only
- 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine has the functional parent linoleic acidCompoundChEBI CHEBI:75069Inferred only
- 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:84822Inferred only
- 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol has the functional parent linoleic acidCompoundChEBI CHEBI:77097Inferred only
- 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:86094Inferred only
- 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:42027Inferred only
- 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol has the functional parent linoleic acidCompoundChEBI CHEBI:75844Inferred only
- 1,3-di-(9Z,12Z)-octadecadienoylglycerol has the functional parent linoleic acidCompoundChEBI CHEBI:75850Inferred only
- 2-(9Z,12Z-octadecadienoyl)-glycerol has the functional parent linoleic acidCompoundChEBI CHEBI:75457Inferred only
- 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:76084Inferred only
- 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine has the functional parent linoleic acidCompoundChEBI CHEBI:76090Inferred only
- 2,3-di-(9Z,12Z)-octadecadienoyl-sn-glycerol has the functional parent linoleic acidCompoundChEBI CHEBI:75854Inferred only
- cholesteryl (9Z,12Z)-octadecadienoate has the functional parent linoleic acidCompoundChEBI CHEBI:41509Inferred only
Statements
142 statements
142 statements · 1 reference database · Subject: linoleic acid · Sources: Human-GEM
- linoleic acid is converted to (13S)-hydroperoxy-(9Z,11E)-octadecadienoateCompoundHuman-GEM MAR02440Inferred only
- linoleic acid is converted to (9S)-hydroperoxy-(10E,12Z)-octadecadienoateCompoundHuman-GEM MAR02437Inferred only
- linoleic acid is metabolised by CYP1A1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP1A1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP1A1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP1A1ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP1A2ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP1A2ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP1A2ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP1A2ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP1B1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP1B1ProteinHuman-GEM MAR02455Inferred only
Show the remaining 130
- linoleic acid is metabolised by CYP1B1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP1B1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2A13ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2A13ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2A13ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2A13ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2A6ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2A6ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2A6ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2A6ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2A7ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2A7ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2A7ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2A7ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2B6ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2B6ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2B6ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2B6ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2C19ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2C19ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2C19ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2C19ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2C8ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2C8ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2C8ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2C8ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2C9ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2C9ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2C9ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2C9ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2D6ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2D6ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2D6ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2D6ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2E1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2E1ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2E1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2E1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2F1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2F1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2F1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2F1ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2J2ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2J2ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2J2ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2J2ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2S1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2S1ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP2S1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2S1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2U1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP2U1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP2U1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP2U1ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP3A4ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP3A4ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP3A4ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP3A4ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP3A43ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP3A43ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP3A43ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP3A43ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP3A5ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP3A5ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP3A5ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP3A5ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP4B1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP4B1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP4B1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP4B1ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP4F11ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP4F11ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP4F11ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP4F11ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP4F12ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP4F12ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP4F12ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP4F12ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP4F8ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP4F8ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is metabolised by CYP4F8ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP4F8ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP4Z1ProteinHuman-GEM MAR02456Inferred only
- linoleic acid is metabolised by CYP4Z1ProteinHuman-GEM MAR02457Inferred only
- linoleic acid is metabolised by CYP4Z1ProteinHuman-GEM MAR02455Inferred only
- linoleic acid is metabolised by CYP4Z1ProteinHuman-GEM MAR02458Inferred only
- linoleic acid is a substrate of ACSBG1ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of ACSBG1ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of ACSBG2ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of ACSBG2ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of ACSL1ProteinHuman-GEM MAR02786Inferred only
- linoleic acid is a substrate of ACSL1ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of ACSL1ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of ACSL1ProteinHuman-GEM MAR02802Inferred only
- linoleic acid is a substrate of ACSL3ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of ACSL3ProteinHuman-GEM MAR02786Inferred only
- linoleic acid is a substrate of ACSL3ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of ACSL3ProteinHuman-GEM MAR02802Inferred only
- linoleic acid is a substrate of ACSL4ProteinHuman-GEM MAR02786Inferred only
- linoleic acid is a substrate of ACSL4ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of ACSL4ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of ACSL4ProteinHuman-GEM MAR02802Inferred only
- linoleic acid is a substrate of ACSL5ProteinHuman-GEM MAR02786Inferred only
- linoleic acid is a substrate of ACSL5ProteinHuman-GEM MAR02802Inferred only
- linoleic acid is a substrate of ACSL5ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of ACSL5ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of ACSL6ProteinHuman-GEM MAR02802Inferred only
- linoleic acid is a substrate of ACSL6ProteinHuman-GEM MAR02786Inferred only
- linoleic acid is a substrate of ACSL6ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of ACSL6ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of ALOX15ProteinHuman-GEM MAR02440Inferred only
- linoleic acid is a substrate of ALOX15BProteinHuman-GEM MAR02440Inferred only
- linoleic acid is a substrate of SLC27A2ProteinHuman-GEM MAR02802Inferred only
- linoleic acid is a substrate of SLC27A2ProteinHuman-GEM MAR02991Inferred only
- linoleic acid is a substrate of SLC27A2ProteinHuman-GEM MAR00397Inferred only
- linoleic acid is a substrate of SLC27A4ProteinHuman-GEM MAR07152Inferred only
- linoleic acid is transported by CD36ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP1ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP12ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP2ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP3ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP4ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP5ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP6ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP7ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by FABP9ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by SLC27A1ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by SLC27A3ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by SLC27A4ProteinHuman-GEM MAR00396Inferred only
- linoleic acid is transported by SLC27A6ProteinHuman-GEM MAR00396Inferred only
Reactions
37 reactions
fatty acid0.0001MAM00003e+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010e+0.0001MAM00017e+0.0001MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0001MAM00117e+0.0001MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0001MAM01197e+0.0001MAM01207e+0.0001MAM01235e+0.0001MAM01238e+0.0001(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0082(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582e+0.0001MAM01583e+0.0001(11Z)-eicosenoate+0.0001MAM01585e+0.0041all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.002(8Z,11Z,14Z)-eicosatrienoate+0.0001(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.001(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0001MAM01932e+0.0001MAM02053e+0.0001dodecanoate+0.0001tetracosanoate+0.1535linoleic acid+0.0092alpha-linolenic acid+0.0001MAM02456e+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0338tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613e+0.3837(9Z)-octadecenoate+0.0001MAM02648e+0.3015hexadecanoic acid+0.0522(9Z)-hexadecenoate+0.0001MAM02690e+0.0001MAM02745e+0.046octadecanoate+0.0001MAM02939e+0.0001tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableGO:0005615
Human-GEM MAR00012CC BY 4.0Reference data
MAM02560e0.0048MAM00003e+0.0016(11Z,14Z)-eicosadienoate+0.0016MAM00010e+0.0001MAM00017e+0.0001MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0001MAM00117e+0.0001MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0001MAM01197e+0.0001MAM01207e+0.0001MAM01235e+0.0001MAM01238e+0.0017(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0137(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0007docosanoate+0.0005hexacosanoate+0.0001MAM01582e+0.0002MAM01583e+0.0001(11Z)-eicosenoate+0.0001MAM01585e+0.0046all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0025(8Z,11Z,14Z)-eicosatrienoate+0.0019(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0011eicosanoate+0.0001elaidic acid+0.002(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0048MAM01932e+0.0001MAM02053e+0.0034dodecanoate+0.0012tetracosanoate+0.071linoleic acid+0.0005alpha-linolenic acid+0.0056MAM02456e+0.0005(5Z,8Z,11Z)-eicosatrienoate+0.0283tetradecanoate+0.0003(15Z)-tetracosenoate+0.0001MAM02613e+0.3746(9Z)-octadecenoate+0.0001MAM02648e+0.2949hexadecanoic acid+0.0686(9Z)-hexadecenoate+0.003MAM02690e+0.0001MAM02745e+0.1031octadecanoate+0.0001MAM02939e+0.0002tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableGO:0005615
Human-GEM MAR00015CC BY 4.0Reference data
0.0001MAM00003e+0.0023(11Z,14Z)-eicosadienoate+0.0003MAM00010e+0.0002MAM00017e+0.003MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0004MAM00117e+0.0023MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0045MAM01197e+0.0002MAM01207e+0.001MAM01235e+0.0037MAM01238e+0.0008(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0051(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0002docosanoate+0.0001hexacosanoate+0.0001MAM01582e+0.0002MAM01583e+0.0046(11Z)-eicosenoate+0.0204MAM01585e+0.0012all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0021(8Z,11Z,14Z)-eicosatrienoate+0.0009(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0009eicosanoate+0.0001elaidic acid+0.0009(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0005MAM01932e+0.0001MAM02053e+0.0061dodecanoate+0.0001tetracosanoate+0.1573linoleic acid+0.0073alpha-linolenic acid+0.0001MAM02456e+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.035tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613e+0.383(9Z)-octadecenoate+0.0004MAM02648e+0.2478hexadecanoic acid+0.0395(9Z)-hexadecenoate+0.0039MAM02690e+0.0001MAM02745e+0.0613octadecanoate+0.0001MAM02939e+0.0001tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoateMAM02561e
Reaction pageLeft to rightBalance undeterminableGO:0005615
Human-GEM MAR00016CC BY 4.0Reference data
Transported by SLC27A6 or FABP3 or SLC27A1 or CD36 or SLC27A3 or FABP2 or FABP1 or FABP7 or FABP5 or SLC27A4 or FABP6 or FABP4 and 2 more alternatives
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR00396CC BY 4.0Reference data
ATP+CHEBI:1146900+linoleic acidAMP+(9Z,12Z)-octadecadienoyl-CoA+diphosphate(3-)
Catalysed by ACSL4 or ACSBG1 or ACSL3 or ACSBG2 or SLC27A2 or ACSL1 or ACSL6 or ACSL5
Reaction pageLeft to rightBalancedEC 6.2.1.3GO:0005829
Human-GEM MAR00397CC BY 4.0Reference data
water+(9Z,12Z)-octadecadienoyl-CoACHEBI:1146900+proton+linoleic acid
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2GO:0005829
Human-GEM MAR00398CC BY 4.0Reference data
ATP+water+linoleic acidADP+proton+linoleic acid+phosphate(3-)
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR00399CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0001MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0001(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0024(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0208MAM01585c+0.0005all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0013(8Z,11Z,14Z)-eicosatrienoate+0.0017(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0013(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0048MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.0741linoleic acid+0.0037alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0096tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.122(9Z)-octadecenoate+0.0001MAM02648c+0.64hexadecanoic acid+0.0286(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.082octadecanoate+0.0028MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableGO:0005829
Human-GEM MAR00685CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0016MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0032(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0521(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0217MAM01585c+0.0081all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0023(8Z,11Z,14Z)-eicosatrienoate+0.0018(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0003(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.003MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.281linoleic acid+0.0119alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0024tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.4226(9Z)-octadecenoate+0.0001MAM02648c+0.12hexadecanoic acid+0.0229(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.0384octadecanoate+0.0025MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableGO:0005829
Human-GEM MAR00686CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0011MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0022(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0264(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0194MAM01585c+0.0221all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0141(8Z,11Z,14Z)-eicosatrienoate+0.0038(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0035(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0081MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.278linoleic acid+0.0023alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.003tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.4519(9Z)-octadecenoate+0.0001MAM02648c+0.0849hexadecanoic acid+0.014(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.0584octadecanoate+0.0026MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableGO:0005829
Human-GEM MAR00687CC BY 4.0Reference data
fatty acid0.0005MAM00003c+0.0005(11Z,14Z)-eicosadienoate+0.0005MAM00010c+0.0005MAM00017c+0.0005MAM00019c+0.0005MAM00021c+0.0039MAM00094c+0.0005MAM00104c+0.0005MAM00111c+0.0005MAM00114c+0.0005MAM00115c+0.0005MAM00117c+0.0005MAM00128c+0.0005MAM00132c+0.0005MAM00135c+0.0005MAM00260c+0.0005MAM00265c+0.0005MAM00315c+0.0005MAM00341c+0.0005MAM01197c+0.0005MAM01207c+0.0005MAM01235c+0.0005MAM01238c+0.0011(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0709(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0005docosanoate+0.0005hexacosanoate+0.0005MAM01582c+0.0005MAM01583c+0.0005(11Z)-eicosenoate+0.0271MAM01585c+0.0252all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0228(8Z,11Z,14Z)-eicosatrienoate+0.0056(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0005eicosanoate+0.0005elaidic acid+0.0109(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0036MAM01932c+0.0005MAM02053c+0.0005dodecanoate+0.0005tetracosanoate+0.2479linoleic acid+0.0047alpha-linolenic acid+0.0005MAM02456c+0.0005(5Z,8Z,11Z)-eicosatrienoate+0.0054tetradecanoate+0.0005(15Z)-tetracosenoate+0.0005MAM02613c+0.1143(9Z)-octadecenoate+0.0178MAM02648c+0.2781hexadecanoic acid+0.0105(9Z)-hexadecenoate+0.0005MAM02690c+0.0005MAM02745c+0.1271octadecanoate+0.0026MAM02939c+0.0005tricosanoate+0.0005MAM03051c+0.0005(17Z)-hexacosenoate
Reaction pageReversibleBalance undeterminableGO:0005829
Human-GEM MAR00688CC BY 4.0Reference data
fatty acid0.0005MAM00003c+0.0005(11Z,14Z)-eicosadienoate+0.0005MAM00010c+0.0005MAM00017c+0.0005MAM00019c+0.0005MAM00021c+0.0052MAM00094c+0.0005MAM00104c+0.0005MAM00111c+0.0005MAM00114c+0.0005MAM00115c+0.0005MAM00117c+0.0005MAM00128c+0.0005MAM00132c+0.0005MAM00135c+0.0005MAM00260c+0.0005MAM00265c+0.0005MAM00315c+0.0005MAM00341c+0.0005MAM01197c+0.0005MAM01207c+0.0005MAM01235c+0.0005MAM01238c+0.0007(7Z,10Z,13Z,16Z)-docosatetraenoate+0.2125(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0005docosanoate+0.0005hexacosanoate+0.0005MAM01582c+0.0005MAM01583c+0.0005(11Z)-eicosenoate+0.0285MAM01585c+0.0459all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0411(8Z,11Z,14Z)-eicosatrienoate+0.0067(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0005eicosanoate+0.0005elaidic acid+0.0221(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0011MAM01932c+0.0005MAM02053c+0.0005dodecanoate+0.0005tetracosanoate+0.1312linoleic acid+0.0166alpha-linolenic acid+0.0005MAM02456c+0.0005(5Z,8Z,11Z)-eicosatrienoate+0.0319tetradecanoate+0.0005(15Z)-tetracosenoate+0.0005MAM02613c+0.0619(9Z)-octadecenoate+0.0163MAM02648c+0.1243hexadecanoic acid+0.0327(9Z)-hexadecenoate+0.0005MAM02690c+0.0005MAM02745c+0.1983octadecanoate+0.0025MAM02939c+0.0005tricosanoate+0.0005MAM03051c+0.0005(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableGO:0005829
Human-GEM MAR00689CC BY 4.0Reference data
Where it reaches
10 systems, 25 regions, 129 tissues, 171 transporter routes — routes, not measurements: transporters known to carry linoleic acid are expressed there, and no source reports it arriving.
Loading the model…
Papers screened
265 papers
- Compound
- linoleic acid
- Screened
- 265
- Admitted
- 0
- Discarded
- 14
- Not read
- 251
- Showing
- 200 of 265
Discarded: the wrong intervention10 papers
- NCT00204932intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT00571948intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT00721617intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT01145066intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT01826422intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT02445794intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT03141931intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT03563222intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT04102501intervention×1 — no declared intervention names linoleic acid2026-09-29
- NCT04312932intervention×1 — no declared intervention names linoleic acid2026-09-29
Discarded: another reason, stated per paper3 papers
- NCT00908791design×1 — allocation NA -- not randomised2026-09-29
- NCT02410161design×1 — allocation NA -- not randomised2026-09-29
- NCT02433977design×1 — allocation NA -- not randomised2026-09-29
Discarded: no extractable result1 paper
- NCT01251887declared_contrast×16 — no posted analysis compares a linoleic acid arm with a placebo/no-intervention arm and carries a p-value (Diet A: Low Omega-3 (n-3) + High Linoleic Acid (LA)=EXPERIMENTAL+subject, Diet B: Low Omega-3 (n-3) + Low Linoleic Acid (LA)=EXPERIMENTAL+subject, Diet C: High Omega-3 (n-3) + Low Linoleic Acid2026-09-29
Not read yet251 papers
- PMID:114431972026-09-29
- PMID:150287332026-09-29
- PMID:125628752026-09-29
- PMID:111040112026-09-29
- PMID:115255912026-09-29
- PMID:121542682026-09-29
- PMID:123243032026-09-29
- PMID:127915002026-09-29
- PMID:162107222026-09-29
- PMID:165568502026-09-29
- PMID:176167802026-09-29
- PMID:176442932026-09-29
and 239 more.