CHEBI:16523
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
452 compounds within 3 steps: 2 in 1, 84 in 2, 366 in 3
Two steps
- transport of D-serine and glutamine (cytosol to extracellular)
- L-aspartate(in) + L-glutamine(out) = L-aspartate(out) + L-glutamine(in)
Catalysed by SLC3A2, SLC7A10, SLC7A13extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
- transport of D-serine and glutamine (cytosol to extracellular)
- D-serine(in) + L-glutamine(out) + Na(+)(out) = D-serine(out) + L-glutamine(in) + Na(+)(in)
Catalysed by SLC3A2, SLC7A10, SLC1A5extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes
- transport of D-serine and glycine (cytosol to extracellular)
- succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA
Catalysed by SLC3A2, SLC7A10, ALAS1, ALAS2extracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- bile acid-CoA: amino acid N-acyltransferase
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol, peroxisomeOne of 3 routes
- transport of D-serine and glycine (cytosol to extracellular)
- glycine + 2-oxoglutarate = glyoxylate + L-glutamate
Catalysed by SLC3A2, SLC7A10, AADATextracellular space, cytosolOne of 11 routes
- transport of D-serine and glycine (cytosol to extracellular)
- bile acid-CoA:amino acid N-acyltransferase (glycine)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosolOne of 2 routes
Catalysed by SLC3A2, SLC7A10, GCATextracellular space, cytosol, mitochondrial matrix
- transport of D-serine and glutamine (cytosol to extracellular)
- transport of glutamine and ornithine (cytosol to extracellular)
Catalysed by SLC3A2, SLC7A10, SLC7A6extracellular space, cytosolOne of 7 routes
- transport of D-serine and glycine (cytosol to extracellular)
- dihydrolipoyl dehydrogenase ([protein]-N6-(lipoyl)lysine)
Catalysed by SLC3A2, SLC7A10, GLDC, GCSHextracellular space, cytosol, mitochondrial matrix
- transport of D-serine and glycine (cytosol to extracellular)
- sarcosine + O2 + H2O = formaldehyde + glycine + H2O2
Catalysed by SLC3A2, SLC7A10, PIPOXextracellular space, cytosolOne of 2 routes
- transport of D-serine and glycine (cytosol to extracellular)
- (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
Catalysed by SLC3A2, SLC7A10, SHMT1, SHMT2extracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- an acyl-CoA + glycine = an N-acylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL3, GLYAT and 1 moreextracellular space, cytosol
Catalysed by SLC3A2, SLC7A10, GATMextracellular space, cytosolOne of 2 routes
- transport of D-serine and glutamine (cytosol to extracellular)
- transport of glutamine and methionine (cytosol to extracellular)
Catalysed by SLC3A2, SLC7A10, SLC7A5extracellular space, cytosolOne of 12 routes
- transport of D-serine and glutamine (cytosol to extracellular)
- transport of glutamine and tryptophan (cytosol to extracellular)
Catalysed by SLC3A2, SLC7A10, SLC7A5extracellular space, cytosolOne of 9 routes
- transport of D-serine and glycine (cytosol to extracellular)
- gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
Catalysed by SLC3A2, SLC7A10, GSSextracellular space, cytosol
- transport of D-serine and glutamine (cytosol to extracellular)
- L-threonine(in) + L-glutamine(out) + Na(+)(out) = L-threonine(out) + L-glutamine(in) + Na(+)(in)
Catalysed by SLC3A2, SLC7A10, SLC1A5extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes
Catalysed by SLC3A2, SLC7A10, KYAT1extracellular space, cytosolOne of 14 routes
- transport of D-serine and glutamine (cytosol to extracellular)
- L-aspartate:L-glutamine amido-ligase (AMP-forming)
Catalysed by SLC3A2, SLC7A10, ASNSextracellular space, cytosolOne of 14 routes
- transport of D-serine and glutamine (cytosol to extracellular)
- transport of glutamine and phenylalanine (cytosol to extracellular)
Catalysed by SLC3A2, SLC7A10, SLC7A5extracellular space, cytosolOne of 14 routes
- transport of D-serine and glutamine (cytosol to extracellular)
- HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
Catalysed by SLC3A2, SLC7A10, CADextracellular space, cytosolOne of 2 routes
- transport of D-serine and glycine (cytosol to extracellular)
- L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
Catalysed by SLC3A2, SLC7A10, AADATextracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- N(omega),N(omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine
Catalysed by SLC3A2, SLC7A10, AGXT2extracellular space, cytosol
- transport of D-serine and glutamine (cytosol to extracellular)
- phosphoribosyl pyrophosphate amidotransferase (glutamine)
Catalysed by SLC3A2, SLC7A10, PPATextracellular space, cytosolOne of 2 routes
- transport of D-serine and glutamine (cytosol to extracellular)
- D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
Catalysed by SLC3A2, SLC7A10, GFPT2, GFPT1extracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL2extracellular space, cytosolOne of 2 routes
Catalysed by SLC3A2, SLC7A10extracellular space, cytosol, mitochondrial matrixOne of 2 routes
- transport of D-serine and glycine (cytosol to extracellular)
- (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
Catalysed by SLC3A2, SLC7A10, AGXT2extracellular space, cytosol
Catalysed by SLC3A2, SLC7A10extracellular space, cytosolOne of 2 routes
- transport of D-serine and glycine (cytosol to extracellular)
- tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL2extracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol
- transport of D-serine and glycine (cytosol to extracellular)
- hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol
- transport of D-serine and glutamine (cytosol to extracellular)
- an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL1B, GLYATL1extracellular space, cytosol
Three steps
- transport of D-serine and glutamine (cytosol to extracellular)
- transport of glutamine and tryptophan (cytosol to extracellular)
- beta-carboline hydrolysis
Catalysed by SLC3A2, SLC7A10, SLC7A5extracellular space, cytosol
- transport of D-serine and glutamine (cytosol to extracellular)
- Transport of L-Glutamine by Atb0 Transporter
- Carnitine Transport by Atb0
Catalysed by SLC3A2