N-tetradecanoyl-(2S)-hydroxyglycine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

226 compounds within 3 steps: 4 in 1, 32 in 2, 190 in 3

Three steps

11-cis-retinyl tetradecanoateReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. 11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA
Catalysed by PAM, GLYATL2, AWAT2
9-cis-retinyl tetradecanoateReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. 9-cis-retinol + tetradecanoyl-CoA = 9-cis-retinyl tetradecanoate + CoA
Catalysed by PAM, GLYATL2, AWAT2
13-cis-retinyl tetradecanoateReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. 13-cis-retinol + tetradecanoyl-CoA = 13-cis-retinyl tetradecanoate + CoA
Catalysed by PAM, GLYATL2, AWAT2
all-trans-retinyl tetradecanoateReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. all-trans-retinol + tetradecanoyl-CoA = all-trans-retinyl tetradecanoate + CoA
Catalysed by PAM, GLYATL2, AWAT2
tetradecyl tetradecanoateReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. tetradecan-1-ol + tetradecanoyl-CoA = tetradecyl tetradecanoate + CoA
Catalysed by PAM, GLYATL2, AWAT2
N(2)-(1-hydroxy-2-oxoethyl)-dGTPReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glycolate + NADP(+) = glyoxylate + NADPH + H(+)
3. N(2)-(1-hydroxy-2-oxoethyl)-dGTP + H2O = dGTP + glycolate + H(+)
Catalysed by PAM, GRHPR, PARK7
N(2)-(1-hydroxy-2-oxoethyl)-GMPReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glycolate + NADP(+) = glyoxylate + NADPH + H(+)
3. N(2)-(1-hydroxy-2-oxoethyl)-GMP + H2O = glycolate + GMP + H(+)
Catalysed by PAM, GRHPR, PARK7
N-hexadecanoylglycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. hexadecanoyl-CoA + glycine = N-hexadecanoylglycine + CoA + H(+)
Catalysed by PAM, GLYATL2, GLYATL3
N-dodecanoylglycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. dopamine + 2 L-ascorbate + O2 = (R)-noradrenaline + 2 monodehydro-L-ascorbate radical + H2O
3. N-dodecanoylglycine + 2 L-ascorbate + O2 = N-dodecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
Catalysed by PAM, DBHOne of 3 routes
N-(9Z,12Z,15Z)-octadecatrienoylglycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. dopamine + 2 L-ascorbate + O2 = (R)-noradrenaline + 2 monodehydro-L-ascorbate radical + H2O
3. N-(9Z,12Z,15Z)-octadecatrienoylglycine + 2 L-ascorbate + O2 = N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
Catalysed by PAM, DBHOne of 2 routes
N-decanoylglycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. dopamine + 2 L-ascorbate + O2 = (R)-noradrenaline + 2 monodehydro-L-ascorbate radical + H2O
3. N-decanoylglycine + 2 L-ascorbate + O2 = N-decanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
Catalysed by PAM, DBHOne of 3 routes
N-octanoylglycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. dopamine + 2 L-ascorbate + O2 = (R)-noradrenaline + 2 monodehydro-L-ascorbate radical + H2O
3. N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
Catalysed by PAM, DBHOne of 3 routes
octanamideReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
3. N-octanoyl-(2S)-hydroxyglycine = octanamide + glyoxylate
Catalysed by PAM
(9Z,12Z,15Z)-octadecatrienamideReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. N-(9Z,12Z,15Z)-octadecatrienoylglycine + 2 L-ascorbate + O2 = N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
3. N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine = (9Z,12Z,15Z)-octadecatrienamide + glyoxylate
Catalysed by PAM
N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. 5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)
Catalysed by PAM, GLYATL2, GART
L-cystine-bis-glycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
Catalysed by PAM, GLYATL2, DPEP1, DPEP2
glycyldehydrophenylalanineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine
Catalysed by PAM, GLYATL2, DPEP1
an N-(fatty acyl)-glycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)
Catalysed by PAM, GLYATL2
N-(9Z,12Z-octadecadienoyl)-glycineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
Catalysed by PAM, GLYATL2
acetylpyruvateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + L-alanine = glycine + pyruvate
3. acetylpyruvate + H2O = acetate + pyruvate + H(+)
Catalysed by PAM, AGXT, AGXT2, FAHD1
all-trans-retinoic acidReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + L-alanine = glycine + pyruvate
3. transport of pyruvate and retinoate (cytosol to extracellular)
Catalysed by PAM, AGXT, AGXT2, SLC16A4 and 5 moreextracellular space, cytosolOne of 2 routes
palmitoyl-CoAReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. fatty-acyl-CoA synthase (N-C16:0CoA)
Catalysed by PAM, GLYATL2cytosol
propionyl-CoAReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
3. 2-oxobutyrate oxidation
Catalysed by PAM, AGXT2cytosol
CHEBI:15570Reach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of D-alanine and glycine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC3A2, SLC7A10extracellular space, cytosolOne of 2 routes
L-leucineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of glycine and leucine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC7A5extracellular space, cytosolOne of 7 routes
CHEBI:15611Reach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. S-Adenosyl-L-methionine:glycine N-methyltransferase
Catalysed by PAM, GLYATL2, GNMTcytosol
CHEBI:15699Reach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of glycine and homoserine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC7A5extracellular space, cytosolOne of 4 routes
formateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + O2 + H2O = oxalate + H2O2 + H(+)
3. oxalate(in) + formate(out) = oxalate(out) + formate(in)
Catalysed by PAM, HAO1, SLC26A6inner side of the membrane, outer side of the membraneOne of 2 routes
malonateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
3. malonate(out) + (S)-malate(in) = malonate(in) + (S)-malate(out)
Catalysed by PAM, CLYBL, SLC25A10inner side of the membrane, outer side of the membraneOne of 2 routes
CHEBI:15971Reach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of glycine and histidine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC7A6extracellular space, cytosolOne of 2 routes
homogentisateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
3. 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating)
Catalysed by PAM, AADAT, HPDcytosolOne of 2 routes
sulfateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + O2 + H2O = oxalate + H2O2 + H(+)
3. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
Catalysed by PAM, HAO1, SLC25A14, SLC26A2 and 3 moreinner side of the membrane, outer side of the membraneOne of 6 routes
2-methyl-3-oxopropanoic acidReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + L-alanine = glycine + pyruvate
3. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
Catalysed by PAM, AGXT, AGXT2mitochondrial matrix
L-citrullineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of citrulline and glycine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC7A9, SLC3A1 and 1 moreextracellular space, cytosol
L-valineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of glycine and valine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC7A5extracellular space, cytosolOne of 4 routes
oxaloacetateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
3. transport of malate and OAA (cytosol to mitochondria)
Catalysed by PAM, CLYBLmitochondrial matrix, cytosolOne of 9 routes
L-arginineReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of arginine and glycine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC7A6extracellular space, cytosolOne of 2 routes
CHEBI:16523Reach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of D-serine and glycine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC3A2, SLC7A10extracellular space, cytosolOne of 2 routes
protein polypeptide chainReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. PROTEIN_BS
Catalysed by PAM, GLYATL2cytosol
(S)-lactateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + L-alanine = glycine + pyruvate
3. (S)-lactate + NAD(+) = pyruvate + NADH + H(+)
Catalysed by PAM, AGXT, AGXT2, LDHA and 4 more
9-hydroxytetradecanoateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. tetradecamide + H2O = tetradecanoate + NH4(+)
3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PAM, FAAH, CYP4Z1
10-hydroxytetradecanoateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. tetradecamide + H2O = tetradecanoate + NH4(+)
3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PAM, FAAH, CYP4Z1
12-hydroxytetradecanoateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. tetradecamide + H2O = tetradecanoate + NH4(+)
3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 12-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PAM, FAAH, CYP4Z1
11-hydroxytetradecanoateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. tetradecamide + H2O = tetradecanoate + NH4(+)
3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 11-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PAM, FAAH, CYP4Z1
2-oxoglutaramateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + L-alanine = glycine + pyruvate
3. L-Glutamine:pyruvate aminotransferase
Catalysed by PAM, AGXT, AGXT2, KYAT1cytosolOne of 3 routes
enol-phenylpyruvateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + L-phenylalanine = 3-phenylpyruvate + glycine
3. 3-phenylpyruvate = enol-phenylpyruvate
Catalysed by PAM, AADAT, MIF
3-fumarylpyruvateReach from here →
1. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate
2. glyoxylate + L-alanine = glycine + pyruvate
3. 3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)
Catalysed by PAM, AGXT, AGXT2, FAHD1
CHEBI:16856Reach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. dopamine + 2 L-ascorbate + O2 = (R)-noradrenaline + 2 monodehydro-L-ascorbate radical + H2O
3. transport of GSH and noradrenaline (cytosol to extracellular)
Catalysed by PAM, DBH, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 3 routes
CHEBI:16857Reach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. transport of glycine and threonine (cytosol to extracellular)
Catalysed by PAM, GLYATL2, SLC3A2, SLC7A5 and 1 moreextracellular space, cytosolOne of 4 routes
glyoxylic acidReach from here →
1. N-tetradecanoylglycine + 2 L-ascorbate + O2 = N-tetradecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
3. glycine:oxygen oxidoreductase (deaminating)
Catalysed by PAM, GLYATL2, DAOperoxisomeOne of 4 routes