A

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. L-Cysteine:2-oxoglutarate aminotransferase

Catalysed by MOCOS, GOT2, GOT1cytosolOne of 3 routes

1. N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2
2. alcohol dehydrogenase (formaldehyde)

Catalysed by KDM1A, KDM1B, ADH1C, ADH1A and 4 morecytosol

1. A + NADH + H(+) = AH2 + NAD(+)
2. N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)

Catalysed by AIFM1, PYROXD1, CDK5RAP1One of 10 routes

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. transport of cysteine and tryptophan (cytosol to extracellular)

Catalysed by MOCOS, SLC7A5extracellular space, cytosolOne of 4 routes

1. A + NADH + H(+) = AH2 + NAD(+)
2. L-selenocysteine + AH2 = hydrogenselenide + L-alanine + A + H(+)

Catalysed by AIFM1, PYROXD1, SCLYOne of 17 routes

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. transport of asparagine and cysteine (cytosol to extracellular)

Catalysed by MOCOS, SLC7A5extracellular space, cytosolOne of 4 routes

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. transport of cysteine and phenylalanine (cytosol to extracellular)

Catalysed by MOCOS, SLC7A5extracellular space, cytosolOne of 6 routes

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. L-glutamate:L-cysteine gamma-ligase (ADP-forming)

Catalysed by MOCOS, GCLC, GCLMcytosolOne of 2 routes

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. 2 L-cysteine = S-sulfanyl-L-cysteine + L-alanine

Catalysed by MOCOS, CARS2

1. (R)-malate + A = oxaloacetate + AH2
2. oxaloacetate + GTP = phosphoenolpyruvate + GDP + CO2

Catalysed by D2HGDH, PCK1, PCK2

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. (R)-4'-phosphopantothenate:L-cysteine ligase

Catalysed by MOCOS, PPCScytosolOne of 4 routes

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. L-Cysteine:oxygen oxidoreductase

Catalysed by MOCOS, CDO1cytosolOne of 2 routes

1. all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2
2. Lecithin Retinol Acyltransferase

Catalysed by RETSAT, LRATcytosolOne of 4 routes

1. A + NADH + H(+) = AH2 + NAD(+)
2. a 2,3-saturated acyl-CoA + A = a 2,3-dehydroacyl-CoA + AH2

Catalysed by AIFM1, PYROXD1, ACAD10One of 2 routes

1. all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2
2. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol = all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol

Catalysed by RETSAT, PNPLA4, PNPLA2

1. all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2
2. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol = all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol

Catalysed by RETSAT, PNPLA4, PNPLA2

1. all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2
2. all-trans-retinol + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine

Catalysed by RETSAT, LRAT

1. A + NADH + H(+) = AH2 + NAD(+)
2. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9R)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS1, PTGS2

1. all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2
2. retinol binding protein (retinol)

Catalysed by RETSAT, RBP1, RBP2cytosolOne of 2 routes

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

Catalysed by AIFM1, PYROXD1, MOCOSOne of 3 routes

1. A + NADH + H(+) = AH2 + NAD(+)
2. 2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. prostaglandin G1 + AH2 = prostaglandin H1 + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 = 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS2

1. A + NADH + H(+) = AH2 + NAD(+)
2. (9Z,12Z)-octadecadienoate + AH2 + O2 = (13S)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O

Catalysed by AIFM1, PYROXD1, PTGS1, PTGS2

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. transport of cysteine and tryptophan (cytosol to extracellular)
3. beta-carboline hydrolysis

Catalysed by MOCOS, SLC7A5extracellular space, cytosol

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
2. N-acetylglutamate synthase (N-acetyl-L-cysteine)
3. Carnitine O-Palmitoyltransferase

Catalysed by MOCOS, NAGS and 1 more