Compound
(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
A 15-HETE(1−) that is the conjugate base of 15(R)-HETE(1−), obtained by deprotonation of the carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:78837), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C20H31O3
- Mass
- 319.465 g/mol
- Charge
- -1
- InChIKey
- JSFATNQSLKRBCI-UDQWCNDOSA-M
- SMILES
- CCCCC[C@@H](O)/C=C/C=CC/C=CC/C=CCCCC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate · Sources: Rhea
- (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is metabolised by CYP2C9ProteinRhea RHEA:52496Inferred only
- (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is a substrate of PLA2G4AProteinRhea RHEA:53696Inferred only
- (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is a substrate of PTGS2ProteinRhea RHEA:50856Inferred only
Reactions
3 reactions
(5Z,8Z,11Z,14Z)-eicosatetraenoate+AH2+dioxygen(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate+A+water
Catalysed by PTGS2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:50856CC BY 4.0Reference data
(5Z,8Z,11Z,14Z)-eicosatetraenoate+reduced [NADPH--hemoprotein reductase]+dioxygen(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP2C9
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:52496CC BY 4.0Reference data
2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine+water(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate+sn-glycerol 3-phosphocholine+hydron
Catalysed by PLA2G4A
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:53696CC BY 4.0Reference data
Other names
3 names
Resolves to: (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
- Also called
- (5Z,8Z,11Z,13E,15R)-15-hydroxyeicosatetraenoate(5Z,8Z,11Z,13E,15R)-15-hydroxyicosatetraenoate15(R)-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoate