Compound
(9R)-hydroxy-(10E,12Z)-octadecadienoate
A hydroxy fatty acid anion obtained by deprotonation of the carboxy group of 9(R)-HODE; major species at pH 7.3.
Definition from ChEBI (CHEBI:77895), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C18H31O3
- Mass
- 295.443 g/mol
- Charge
- -1
- InChIKey
- NPDSHTNEKLQQIJ-WXUVIADPSA-M
- SMILES
- CCCCC/C=CC=C[C@H](O)CCCCCCCC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Chemical structure
- (9S)-hydroxy-(10E,12Z)-octadecadienoate is the enantiomer of (9R)-hydroxy-(10E,12Z)-octadecadienoateCompoundChEBI CHEBI:77852Inferred only
Statements
3 statements
3 statements · 1 reference database · Subject: (9R)-hydroxy-(10E,12Z)-octadecadienoate · Sources: Rhea
- (9R)-hydroxy-(10E,12Z)-octadecadienoate is metabolised by CYP2C9ProteinRhea RHEA:52504Inferred only
- (9R)-hydroxy-(10E,12Z)-octadecadienoate is a substrate of PTGS1ProteinRhea RHEA:75447Inferred only
- (9R)-hydroxy-(10E,12Z)-octadecadienoate is a substrate of PTGS2ProteinRhea RHEA:75447Inferred only
Reactions
2 reactions
(9Z,12Z)-octadecadienoate+reduced [NADPH--hemoprotein reductase]+dioxygen(9R)-hydroxy-(10E,12Z)-octadecadienoate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP2C9
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:52504CC BY 4.0Reference data
(9Z,12Z)-octadecadienoate+AH2+dioxygen(9R)-hydroxy-(10E,12Z)-octadecadienoate+A+water
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:75447CC BY 4.0Reference data
Other names
5 names
Resolves to: (9R)-hydroxy-(10E,12Z)-octadecadienoate
- Also called
- (9R)-H-(10E,12Z)-ODE(9R)-HODE(9R)-hydroxy(10E,12Z)-octadecadienoate(1-)(9R)-hydroxy(10E,12Z)-octadecadienoate(1−)
- Systematic name
- (9R,10E,12Z)-9-hydroxyoctadeca-10,12-dienoate