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Proteins/UNIPROT:Q86TU7
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin..
Function from UniProtKB (Q86TU7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
47 statements
47 statements · 5 reference databases · Subject: SETD3 · Sources: Bgee, gene ontology, Hetionet, Reactome, WikiPathways
1 reaction
L-histidyl-[protein]+S-adenosyl-L-methionineN(tele)-methyl-L-histidyl-[protein]+S-adenosyl-L-homocysteine+hydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:19369CC BY 4.0Reference data
4 names
Resolves to: SETD3