Proteins/UNIPROT:Q96KG9

SCYL1

ProteinUNIPROT:Q96KG9

Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum. Involved in the maintenance of the Golgi apparatus morphology..

[Isoform 6]: Acts as a transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region..

Function from UniProtKB (Q96KG9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

acute infantile liver failure-cerebellar ataxia-peripheral sensory motor neuropathy syndrome has a germline basis in SCYL1DiseaseGenCC HGNC:14372|MONDO:0014744Inferred only

Statements

26 statements

26 statements · 2 reference databases · Subject: SCYL1 · Sources: Hetionet, WikiPathways

Order

GAS2L1 covaries with SCYL1ProteinHetionet hetionet:covaries:10634-57410Inferred only
KDM5C covaries with SCYL1ProteinHetionet hetionet:covaries:57410-8242Inferred only
LRP1 covaries with SCYL1ProteinHetionet hetionet:covaries:4035-57410Inferred only
NAT14 covaries with SCYL1ProteinHetionet hetionet:covaries:57106-57410Inferred only
NCKAP5L covaries with SCYL1ProteinHetionet hetionet:covaries:57410-57701Inferred only
PCNX3 covaries with SCYL1ProteinHetionet hetionet:covaries:399909-57410Inferred only
PRPF40B covaries with SCYL1ProteinHetionet hetionet:covaries:25766-57410Inferred only
PSMD10 covaries with SCYL1ProteinHetionet hetionet:covaries:5716-57410Inferred only
SPOUT1 covaries with SCYL1ProteinHetionet hetionet:covaries:51490-57410Inferred only
SST covaries with SCYL1ProteinHetionet hetionet:covaries:57410-6750Inferred only
THAP7 covaries with SCYL1ProteinHetionet hetionet:covaries:57410-80764Inferred only
SCYL1 covaries with ZCCHC17ProteinHetionet hetionet:covaries:51538-57410Inferred only

Show the remaining 14

CD93 interacts with SCYL1ProteinHetionet hetionet:interacts:22918-57410Inferred only
CDC25A interacts with SCYL1ProteinHetionet hetionet:interacts:57410-993Inferred only
CHD1L interacts with SCYL1ProteinHetionet hetionet:interacts:57410-9557Inferred only
COIL interacts with SCYL1ProteinHetionet hetionet:interacts:57410-8161Inferred only
SCYL1 interacts with GORABProteinHetionet hetionet:interacts:57410-92344Inferred only
SCYL1 participates in miR targeted genes in leukocytesPathwayWikiPathways WP2003Inferred only
SCYL1 participates in miR targeted genes in lymphocytesPathwayWikiPathways WP2004Inferred only
SCYL1 participates in miR targeted genes in muscle cellPathwayWikiPathways WP2005Inferred only
SCYL1 decreases the expression of ACAA1ProteinHetionet hetionet:regulates:57410-30Inferred only
SCYL1 decreases the expression of LOXL1ProteinHetionet hetionet:regulates:57410-4016Inferred only
SCYL1 decreases the expression of NGRNProteinHetionet hetionet:regulates:57410-51335Inferred only
SCYL1 decreases the expression of RPA3ProteinHetionet hetionet:regulates:57410-6119Inferred only
SCYL1 decreases the expression of STEAP1ProteinHetionet hetionet:regulates:57410-26872Inferred only
SCYL1 increases the expression of ZNF672ProteinHetionet hetionet:regulates:57410-79894Inferred only

Other names

11 names

Resolves to: SCYL1

Also called: Coated vesicle-associated kinase of 90 kDaCVAK90GKLPNTKLSCY1-like protein 1TAPKTEIFTelomerase regulation-associated proteinTelomerase transcriptional element-interacting factorTeratoma-associated tyrosine kinaseTRAP

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