Proteins/UNIPROT:O75368

SH3BGRL

ProteinUNIPROT:O75368

Appears to function as an adapter protein that bridges proteins together or proteins with mRNAs. May function as a ubiquitin ligase-substrate adapter. Additionally, associates with translating cytoplasmic ribosomes and may promote the expression of specific mRNAs..

Function from UniProtKB (O75368), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

17 statements

17 statements · 2 reference databases · Subject: SH3BGRL · Sources: gene ontology, Hetionet

Order

SH3BGRL covaries with PSMD4ProteinHetionet hetionet:covaries:5710-6451Inferred only
SH3BGRL covaries with SERP1ProteinHetionet hetionet:covaries:27230-6451Inferred only
EGFR interacts with SH3BGRLProteinHetionet hetionet:interacts:1956-6451Inferred only
SH3BGRL interacts with UBCProteinHetionet hetionet:interacts:6451-7316Inferred only
SH3BGRL regulates positive regulation of cytoplasmic translational initiationBiological processgene ontology O75368|GO:1904690Inferred only
BECN1 decreases the expression of SH3BGRLProteinHetionet hetionet:regulates:8678-6451Inferred only
CFLAR decreases the expression of SH3BGRLProteinHetionet hetionet:regulates:8837-6451Inferred only
GBP2 increases the expression of SH3BGRLProteinHetionet hetionet:regulates:2634-6451Inferred only
LOXL1 decreases the expression of SH3BGRLProteinHetionet hetionet:regulates:4016-6451Inferred only
PFDN2 increases the expression of SH3BGRLProteinHetionet hetionet:regulates:5202-6451Inferred only
PHB1 increases the expression of SH3BGRLProteinHetionet hetionet:regulates:5245-6451Inferred only
RXRG increases the expression of SH3BGRLProteinHetionet hetionet:regulates:6258-6451Inferred only

Show the remaining 5

SOX4 decreases the expression of SH3BGRLProteinHetionet hetionet:regulates:6659-6451Inferred only
TBXA2R decreases the expression of SH3BGRLProteinHetionet hetionet:regulates:6915-6451Inferred only
VRK2 increases the expression of SH3BGRLProteinHetionet hetionet:regulates:7444-6451Inferred only
YAP1 increases the expression of SH3BGRLProteinHetionet hetionet:regulates:10413-6451Inferred only
ZIM3 increases the expression of SH3BGRLProteinHetionet hetionet:regulates:114026-6451Inferred only

Other names

2 names

Resolves to: SH3BGRL

Also called: Adapter SH3BGRLSH3 domain-binding glutamic acid-rich-like protein 1

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